Evidence map›Paper›PMID 40147775›Full record

ArticleThe Journal of biological chemistry2025

Spectroscopy and crystallography define carotenoid oxygenases as a new subclass of mononuclear non-heme Fe

Dory E DeWeese, Michael P Everett, Jeffrey T Babicz, Anahita Daruwalla, Edward I Solomon, Philip D Kiser

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dory E DeWeeseDepartment of Chemistry, Stanford University, Stanford, California, USA.
Michael P EverettDepartment of Physiology & Biophysics, University of California, Irvine School of Medicine, Irvine, California, USA.
Jeffrey T BabiczDepartment of Chemistry, Stanford University, Stanford, California, USA; SLAC National Accelerator Laboratory, Stanford University, Menlo Park, California, USA.
Anahita DaruwallaDepartment of Physiology & Biophysics, University of California, Irvine School of Medicine, Irvine, California, USA.
Edward I SolomonDepartment of Chemistry, Stanford University, Stanford, California, USA; SLAC National Accelerator Laboratory, Stanford University, Menlo Park, California, USA. Electronic address: solomone@stanford.edu.
Philip D KiserDepartment of Physiology & Biophysics, University of California, Irvine School of Medicine, Irvine, California, USA; Research Service, VA Long Beach Healthcare System, Long Beach, California, USA. Electronic address: pkiser@uci.edu.

Funding

User Training and OutreachP30GM124165 · NIGMS · CORNELL UNIVERSITY · PI STEVEN E EALICK · 2018 to 2026
$34.2M
X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
Spectroscopic Characterization of Oxygen Intermediates in Non-heme and Heme Iron EnzymesR35GM145202 · NIGMS · STANFORD UNIVERSITY · PI EDWARD I SOLOMON · 2022 to 2026
$2.0M
O-O Bond Activation (and Formation) at Bimetallic Enzyme Active SitesR35GM131721 · NIGMS · UNIVERSITY OF MINNESOTA · PI QUE, LAWRENCE · 2019 to 2023
$1.7M
BLRD VA I01 BX004939BLRD VA IK6 BX006800NIGMS NIH HHS P30 GM124165NIGMS NIH HHS P41 GM103393NIGMS NIH HHS R35 GM131721NIGMS NIH HHS R35 GM145202
6 · The paper itself

Abstract

Carotenoid cleavage dioxygenases (CCDs) are non-heme Fe

Indexed as

DioxygenasesIronNeurospora crassaBiocatalysisCrystallography, X-RayHemeModels, MolecularNitric OxideProtein Structure, TertiarySpectrophotometrySubstrate Specificitycarotenoid cleavage dioxygenase 1DioxygenasesHemeIronNitric Oxidecarotenoiddioxygenaseironisoeugenolnitric oxidepiceatannolstilbene

Identifiers

PMID40147775
PMCPMC12051055

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.