Evidence map›Paper›PMID 40146901›Full record

ArticleInorganic chemistry2025

Luminescent Iridium-Peptide Nucleic Acid Bioconjugate as Photosensitizer for Singlet Oxygen Production toward a Potential Dual Therapeutic Agent.

Rosa Maria Dell'Acqua, Veronica Schifano, Maria Vittoria Dozzi, Laura D'Alfonso, Monica Panigati, Paola Rusmini, Margherita Piccolella, Angelo Poletti, Silvia Cauteruccio, Daniela Maggioni

Abstract read
In one paragraph

Article in Inorganic chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. DNA-Binding Properties of Iridium(III) Complexes Encompassing Design, Function and Biophysical Assessments.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rosa Maria Dell'AcquaDipartimento di Chimica, Università degli Studi di Milano, Via Golgi 19, Milano 20133, Italy.
Veronica SchifanoDipartimento di Chimica, Università degli Studi di Milano, Via Golgi 19, Milano 20133, Italy.ORCID 0009-0008-7359-968X
Maria Vittoria DozziDipartimento di Chimica, Università degli Studi di Milano, Via Golgi 19, Milano 20133, Italy.ORCID 0000-0002-6390-9348
Laura D'AlfonsoDipartimento di Fisica "G. Occhialini", Università degli Studi di Milano-Bicocca, piazza della Scienza 3, Milano 20126, Italy.
Monica PanigatiDipartimento di Chimica, Università degli Studi di Milano, Via Golgi 19, Milano 20133, Italy.ORCID 0000-0001-6649-4865
Paola RusminiDipartimento di Scienze Farmacologiche e Biomolecolari ″Rodolfo Paoletti″, Dipartimento di Eccellenza 2018-2027, Università degli Studi di Milano, Via Balzaretti 9, Milano 20133, Italy.
Margherita PiccolellaDipartimento di Scienze Farmacologiche e Biomolecolari ″Rodolfo Paoletti″, Dipartimento di Eccellenza 2018-2027, Università degli Studi di Milano, Via Balzaretti 9, Milano 20133, Italy.
Angelo PolettiDipartimento di Scienze Farmacologiche e Biomolecolari ″Rodolfo Paoletti″, Dipartimento di Eccellenza 2018-2027, Università degli Studi di Milano, Via Balzaretti 9, Milano 20133, Italy.
Silvia CauteruccioDipartimento di Chimica, Università degli Studi di Milano, Via Golgi 19, Milano 20133, Italy.ORCID 0000-0002-9540-9073
Daniela MaggioniDipartimento di Chimica, Università degli Studi di Milano, Via Golgi 19, Milano 20133, Italy.ORCID 0000-0001-5201-4824

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel bioorganometallic PNA conjugate (

Indexed as

Antineoplastic AgentsCoordination ComplexesIridiumPeptide Nucleic AcidsPhotosensitizing AgentsSinglet OxygenCell SurvivalHeLa CellsHumansMolecular StructureAntineoplastic AgentsCoordination ComplexesIridiumPeptide Nucleic AcidsPhotosensitizing AgentsSinglet Oxygen

Identifiers

PMID40146901
PMCPMC12001249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.