SynthesisPloS one2025
Cognitive impairment and dementia-Are they linked to childhood health and socioeconomic status? A systematic review.
Synthesis in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Dietary Choline and Betaine Intake and 2-year Changes in Cognitive Function in Older Adults With Overweight or Obesity and Metabolic Syndrome: A Prospective Cohort Analysis.The American journal of clinical nutrition · 2026Article
- The role of life-course socioeconomic position in cognitive change and mild cognitive impairment among middle-aged and older US Hispanic/Latinos.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Inequalities in Childhood Healthcare Access Among Racial and Ethnic Groups of Sub-Saharan Africa: A Narrative Review.Children (Basel, Switzerland) · 2026Review
- Childhood adversities and the exposome in dementia risk and brain health.Current opinion in psychiatry · 2026Review
- Associations of childhood economic and psychosocial conditions with later-life cognitive function: a longitudinal analysis of the China health and retirement longitudinal study (2011-2020).BMC public health · 2026Article
- Personality as mechanism: An integrative model of five-factor model personality traits as a mechanism between earlier life factors and cognitive aging.Current opinion in psychology · 2025Review
- Article
- Can socioeconomic disadvantage explain cognitive differences in later life? Insights from the Indonesia family life survey.Frontiers in public health · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDementia is a major public health concern, with its incidence rising as the population ages. Recent studies suggest links between childhood health, socioeconomic status, and later-life cognitive impairment and dementia, though findings remain inconclusive. This systematic review evaluates the influence of childhood health and socioeconomic status on cognitive impairment and dementia. METHOD AND
findingsA systematic search conducted in MEDLINE, CiNAHL, and PsycINFO in December 2024 identified 44 studies matching our inclusion criteria. Findings are presented under five key themes: (1) childhood health, (2) childhood educational attainment, (3) family socioeconomic and educational factors, (4) childhood experiences, and (5) childhood reading habits and social interactions.
conclusionOur results highlight the need for further longitudinal studies to establish causal relationships between early-life risk factors and later cognitive decline. Policymakers should prioritize early childhood development programs that integrate health, nutrition, education, and social support to help mitigate cognitive impairment and dementia in later life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.