Evidence map›Paper›PMID 40146526›Full record

ArticleEuropean geriatric medicine2025

Appropriateness of antibiotic use in nursing homes for suspected urinary tract infections: comparison across five European countries.

Matilde Bøgelund Hansen, Jesper Lykkegaard, Malene Plejdrup Hansen, Carl Llor, Ana Garcia Sangenis, Pia Touboul-Lundgren, Pascale Bruno, Ruta Radzeviciene, Lina Jaruseviciene, Marilena Anastasaki and 8 more

Erratum issuedAbstract readComparative StudyMulticenter Study
In one paragraph

Article in European geriatric medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Matilde Bøgelund HansenDepartment of Clinical Microbiology, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-4659-824X
Jesper LykkegaardAudit Project Odense, Research Unit of General Practice, University of Southern Denmark, Odense, Denmark.ORCID http://orcid.org/0000-0001-9128-6136
Malene Plejdrup HansenAudit Project Odense, Research Unit of General Practice, University of Southern Denmark, Odense, Denmark.ORCID http://orcid.org/0000-0002-8444-1369
Carl LlorInstitut Català de La Salut, Via Roma Health Centre, C. Manso, 19, 3rd Floor, 08015, Barcelona, Spain.ORCID http://orcid.org/0000-0001-6644-717X
Ana Garcia SangenisFundació Institut Universitari Per a La Recerca a L'Atenció Primària de Salut Jordi Gol, Barcelona, Spain.ORCID http://orcid.org/0000-0002-6689-6466
Pia Touboul-LundgrenDepartment of Public Health, Nice University Hospital, Nice, France.ORCID http://orcid.org/0000-0003-1691-5515
Pascale BrunoDepartment of Public Health, Nice University Hospital, Nice, France.ORCID http://orcid.org/0000-0002-8022-114X
Ruta RadzevicieneLtd. Mano Seimos Gydytojas (My Family Doctor), Klapeida, Lithuania.
Lina JarusevicieneLithuanian University of Health Sciences, Kaunas, Lithuania.ORCID http://orcid.org/0000-0003-2171-3635
Marilena AnastasakiClinic of Social and Family Medicine, School of Medicine, University of Crete, Rethymn, Greece.ORCID http://orcid.org/0000-0003-2306-1626
Christos LionisClinic of Social and Family Medicine, School of Medicine, University of Crete, Rethymn, Greece.ORCID http://orcid.org/0000-0002-9324-2839
Anna KowalczykCentre for Family and Community Medicine, The Faculty of Health Sciences, The Medical University of Lodz, Lodz, Poland.ORCID http://orcid.org/0000-0002-7524-2085
Maciek Godycki-ĆwirkoCentre for Family and Community Medicine, The Faculty of Health Sciences, The Medical University of Lodz, Lodz, Poland.ORCID http://orcid.org/0000-0002-9204-5518
Beatriz Gonzalez Lopez-ValcárcelUniversity of Las Palmas de Gran Canaria, Las Palmas, Spain.ORCID http://orcid.org/0000-0002-5571-3257
Fabiana Raynal FlorianoUniversity of Las Palmas de Gran Canaria, Las Palmas, Spain.
Athina ChalkidouDepartment of Clinical Microbiology, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark.ORCID http://orcid.org/0009-0006-9164-8225
Lars BjerrumSection of General Practice and Research Unit for General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-0969-0063
Jette Nygaard JensenDepartment of Clinical Microbiology, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark. jette.nygaard.jensen.01@regionh.dk.ORCID http://orcid.org/0000-0001-5061-9766

Funding

Third Health Programme 900024
6 · The paper itself

Abstract

purposeAntibiotic use is the main driver of bacterial antimicrobial resistance. Urinary tract infections (UTIs), for which antibiotics are often prescribed, are among the most common infections among residents in nursing homes. This study aimed to estimate and compare the appropriateness of antibiotic use for suspected UTIs among nursing home residents across five European countries. Both the decision to treat and the choice of antibiotics used were explored.

methodsThis cross-sectional study used the Audit Project Odense (APO) method. The appropriateness of the treatment decision for UTIs was evaluated according to symptom presentation in residents without indwelling urinary catheters. The choice of antibiotic used for treatment was evaluated according to the first-line antibiotic recommended for the treatment of UTIs in the respective countries. Data were collected through an institutional sign-up questionnaire and a clinical case registration chart. All residents in new or ongoing treatment with systemic antibiotics were registered during a 6-week period between February and April 2022.

resultsA total of 70 nursing homes or wards registered 508 antibiotic treatments for suspected UTIs. The proportion of antibiotics prescribed for UTIs to nursing home residents with no specific UTI symptoms varied from 10% in Poland to 68% in Spain. The proportion of treatments with the first-line choice of antibiotics for UTIs also varied from 28% in France and Poland to 55% in Spain.

conclusionThere was a substantial proportion of potentially inappropriate antibiotic treatments, with notable variation among the countries studied.

Indexed as

Anti-Bacterial AgentsInappropriate PrescribingNursing HomesPractice Patterns, Physicians'Urinary Tract InfectionsAgedAged, 80 and overCross-Sectional StudiesEuropeFemaleHumansMalePolandAnti-Bacterial AgentsAntimicrobial stewardshipClinical decision-makingMedical auditNursing homesQuality of health careUrinary tract infections

Identifiers

PMID40146526
PMCPMC12378316

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.