SynthesisJournal of cancer survivorship : research and practice2026
Effects of digital health on symptoms and health-related quality of life in children and adolescent cancer survivors: a meta-analysis and systematic review.
Synthesis in Journal of cancer survivorship : research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess the effectiveness of digital health on symptoms and health-related quality of life in children and adolescent cancer survivors.
methodsWe searched PubMed, Embase, Web of Science, Cochrane Library, and CINAHL databases on July 11, 2024, to identify randomized controlled trials of the impact of digital health on children and adolescent cancer survivors aged 0-19 years. The Cochrane Risk of Bias Tool version 1.0 was used to evaluate the quality of randomized controlled trials. It was registered in PROSPERO with the number CRD42024526347.
resultsA total of 23 randomized controlled trials were included, of which 18 were meta-analyzed. Compared with usual care, digital health interventions can significantly improve pain (SMD = -0.86, 95% CI: -1.21 to -0.51, P < 0.001), nausea and vomiting (SMD = -0.49, 95% CI: -0.97 to -0.02, P = 0.04), anxiety (SMD = -1.05, 95% CI: -1.60 to -0.50, P = 0.0002), distress (SMD = -0.74, 95% CI: -1.07 to -0.41, P < 0.001), fear (MD = -0.91, 95% CI: -1.40 to -0.42, P = 0.0003), and health-related quality of life (SMD = 1.41, 95% CI: 1.11 to 1.70, P < 0.001) in children and adolescent cancer survivors. However, improvements in fatigue and anger were not significant.
conclusionsOur systematic review provides evidence that digital health interventions have great potential to improve the symptoms and health-related quality of life of children and adolescent cancer survivors. IMPLICATIONS FOR CANCER SURVIVORS: Digital technologies to improve symptoms and health-related quality of life in children and adolescent cancer survivors deserve wider application.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.