Evidence map›Paper›PMID 40146457›Full record

Observational studyObesity surgery2025

Total Alimentary Limb Length Is Not Associated with Weight Loss Following Proximal Roux-en-Y Gastric Bypass.

Vance L Albaugh, Jacob L Weinberg, Danxia Yu, Matthew D Spann, D Brandon Williams, Jason M Samuels, Charles Robb Flynn, Wayne J English

Registry-linked trialAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02872493 (Observational Study of the Effect of Small Intestine Length on Bariatric Surgical Patient Outcomes), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02872493 completednot on this map

Observational Study of the Effect of Small Intestine Length on Bariatric Surgical Patient Outcomes

TypeobservationalSponsorVanderbilt University Medical CenterRan2016 to 2025Enrolled470ConditionsMalnutrition, Obesity, Weight Loss, Micronutrient DeficiencyArmsSmall bowel length measurement
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vance L AlbaughMetamor Institute, Pennington Biomedical Research Center, Baton Rouge, LA, 70808, USA. vance.albaugh@pbrc.edu.
Jacob L WeinbergDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Danxia YuDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37203, USA.
Matthew D SpannDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
D Brandon WilliamsDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Jason M SamuelsDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Charles Robb FlynnDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. robb.flynn@vumc.org.
Wayne J EnglishDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. wayne.english@comcast.net.

Funding

The Gut Microbiota in Metabolic Surgery: A Multi-Ethnic, Multi-Omic, Longitudinal StudyR01DK126721 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI YU, DANXIA · 2021 to 2025
$3.1M
Contribution of Nutrient Delivery Rate to Gut-Brain Axis Signaling in Obesity and Bariatric SurgeryK23DK138261 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Vance L Albaugh · 2024 to 2026
$538k
NIDDK NIH HHS K23 DK138261NIDDK NIH HHS R01 DK126721
6 · The paper itself

Abstract

backgroundStandard Roux-en-Y gastric bypass (RYGB) typically manipulates the proximal portion of the small intestine, leaving a variable and unknown common channel and total alimentary limb length (TALL). Despite high variability in postoperative weight loss, the factors contributing to this variability remain unknown. Given the known variability in small intestinal length, this unmeasured variability in TALL may be associated with weight loss responses.

objectiveTo test the hypothesis that TALL is associated with postoperative weight loss following primary laparoscopic Roux-en-Y gastric bypass (RYGB).

settingVanderbilt University Medical Center; Nashville, Tennessee, USA.

methodsA total of 329 patients were recruited for this observational study and consented to laparoscopic measurement of the entire small intestinal length at the time of primary RYGB. Of these patients, 208 had successful measurement of the small bowel length (SBL) and underwent RYGB with a fixed biliopancreatic limb length (BPL, 50 cm). Common channel length (CCL) was allowed to vary normally to test the association between TALL and postoperative weight loss.

resultsFollow-up rates were 77% at 6 months and 41% at 24 months. Average SBL was 592 cm (min = 390 cm, max = 910 cm), with a standard deviation of 107 cm that led to significant variation in CCL (shortest 190 cm, longest 730 cm). Regression was used to model weight loss and body mass index, as well as percent change from baseline, for each patient given the measured TALL and CCL. Despite significant variation in TALL, there were no clinically significant effects of TALL or CCL on weight loss up to 24 months.

conclusionsWith a fixed BPL, normal variation in TALL does not significantly contribute to weight loss variability following RYGB. Future studies are needed to better understand the importance of intestinal limb lengths in primary and revisional RYGB surgery.

Indexed as

Gastric BypassIntestine, SmallLaparoscopyObesity, MorbidWeight LossAdultBody Mass IndexFemaleFollow-Up StudiesHumansMaleMiddle AgedTennesseeTreatment OutcomeBariatric surgeryCommon channelObservational studyRoux-en-Y gastric bypassSmall bowel lengthWeight loss

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.