ReviewMolecular biotechnology2026
From Motor Proteins to Oncogenic Factors: The Evolving Role of Kinesin Superfamily Proteins in Breast Cancer Development.
Review in Molecular biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Silencing of Kinesin Light Chain 1 Suppresses Aggressive Phenotypes in Cholangiocarcinoma Cells Through Transcriptomic Alterations.International journal of molecular sciences · 2026Article
- A pan-cancer analysis of the oncogenic role of KIF13A in human tumors.Discover oncology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The kinesin family of proteins (KIFs), known for their role as motor proteins, is integral to transporting cargo within cells along microtubule tracks, which is crucial for processes, such as cell division, differentiation, and intracellular communication. Increasing evidence shows that specific KIFs are overexpressed in breast cancer, a change linked to higher tumor aggression and poorer outcomes in patients. KIFs contribute to the cancerous characteristics of breast tumor cells through several mechanisms, including disruptions in spindle assembly during cell division, altered cell motility, and accelerated proliferation. This review summarizes current insights into KIFs' functions in breast cancer pathology and assesses their viability as therapeutic targets. By unraveling the complex involvement of KIFs, the article aims to open pathways for new therapeutic approaches in breast cancer and to promote further study into the cellular pathways that these proteins regulate.
Indexed as
Identifiers
40146390What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.