Evidence map›Paper›PMID 40146371›Full record

ReviewPain and therapy2025

Neurological Deficits Following Regional Anesthesia and Pain Interventions: Reviewing Current Standards of Care.

Salah N El-Tallawy, Rania S Ahmed, Gehan I Salem, Tariq A Alzahrani, Mamdouh M Haddara, Radwa H Ahmed, Mohamed S Nagiub, Abdullah T Alsubaie, Mohamed M Ali, Mahmoud M Elbasha and 1 more

Abstract readReview
In one paragraph

Review in Pain and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Salah N El-TallawyCollege of Medicine, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia. salaheltallawy@yahoo.com.ORCID http://orcid.org/0000-0001-7328-8840
Rania S AhmedCollege of Medicine, Alfaisal University, Riyadh, Saudi Arabia.ORCID http://orcid.org/0009-0004-1865-1167
Gehan I SalemRheumatology, Rehabilitation and Physical Medicine Department, Faculty of Medicine, Assiut University, Assiut, Egypt.
Tariq A AlzahraniCollege of Medicine, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia.ORCID http://orcid.org/0000-0001-8111-5552
Mamdouh M HaddaraKing Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Radwa H AhmedClinical Pathology Department, Faculty of Medicine, Assiut University, Assiut, Egypt.
Mohamed S NagiubCollege of Medicine, Badr University, Cairo, Egypt.
Abdullah T AlsubaieAnesthesia Department, King Saud University Medical City, King Abdulaziz University Hospital, King Saud University, Riyadh, Saudi Arabia.ORCID http://orcid.org/0009-0002-4049-0799
Mohamed M AliAnesthesia Department, King Saud University Medical City, Riyadh, Saudi Arabia.
Mahmoud M ElbashaAnesthesia Department, King Saud University Medical City, Riyadh, Saudi Arabia.
Ahmed A AhmedAnesthesia Department, King Saud University Medical City, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regional anesthesia (RA) has become an integral part of modern anesthesia practice and acute pain management strategies. It provides effective pain relief, reduces opioid consumption, and facilitates enhanced recovery after surgery. However, like any medical intervention, RA is not without risks. RA is associated with potential complications, including neurological deficits which can range from mild and transient to severe and permanent. These neurological deficits may result from non-adherence to established standards of care and deviations from the clinical practice guidelines. An online database search was conducted across multiple websites to identify the relevant articles. The inclusion criteria were articles in English, published between January 2010 and July 2024. The search included various study types, such as case series, observational studies, cross-sectional analyses, cohort studies, longitudinal studies, systematic reviews, and practice guidelines. A total of 38 articles met the inclusion criteria and were included in this comprehensive review which examines the neurological complications associated with regional anesthesia and pain interventions, with a particular focus on how deviations from the standards of care contribute to adverse neurological outcomes. Furthermore, it highlights preventive strategies aimed at minimizing the risks of these complications and improving patient safety.

Indexed as

Acute pain managementAnd standards of careEpidural steroid injectionNerve injuryNeurological complicationsPain interventionsRegional anesthesiaUltrasound-guided regional anesthesia

Identifiers

PMID40146371
PMCPMC12085444

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.