Evidence map›Paper›PMID 40146303›Full record

ReviewMammalian genome : official journal of the International Mammalian Genome Society2025

The mouse resource at National Resource Center for Mutant Mice of China.

Bingzhou Han, Dongshen Chen, Zhong Chen, Ting Wang, Kaiyuan Zi, Rui Feng, Xiaoliu Yang, Ling'en Li, Juan Liang, Xiang Gao

Abstract readReview
In one paragraph

Review in Mammalian genome : official journal of the International Mammalian Genome Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bingzhou HanNational Resource Center for Mutant Mice, GemPharmatech Co., Ltd, Nanjing, China.
Dongshen ChenNational Resource Center for Mutant Mice, Model Animal Research Center of Nanjing University, Nanjing, China.
Zhong ChenNational Resource Center for Mutant Mice, GemPharmatech Co., Ltd, Nanjing, China.
Ting WangNational Resource Center for Mutant Mice, GemPharmatech Co., Ltd, Nanjing, China.
Kaiyuan ZiNational Resource Center for Mutant Mice, GemPharmatech Co., Ltd, Nanjing, China.
Rui FengNational Resource Center for Mutant Mice, GemPharmatech Co., Ltd, Nanjing, China.
Xiaoliu YangNational Resource Center for Mutant Mice, GemPharmatech Co., Ltd, Nanjing, China.
Ling'en LiNational Resource Center for Mutant Mice, GemPharmatech Co., Ltd, Nanjing, China.
Juan LiangNational Resource Center for Mutant Mice, GemPharmatech Co., Ltd, Nanjing, China. liangjuan@gempharmatech.com.
Xiang GaoNational Resource Center for Mutant Mice, GemPharmatech Co., Ltd, Nanjing, China. gaoxiang@nju.edu.cn.

Funding

National Key Research and Development Program of China 2021YFF0702001National Key Research and Development Program of China 2021YFF0702101National Key Research and Development Program of China 2022YFF0710800Technology innovation group project of Foshan 2019 FS0AA-KJ919-4402-0027
6 · The paper itself

Abstract

Mouse models serve as the most important laboratory resource for both biomedical research and preclinical study of drug development. National Resource Center of Mutant Mice (NRCMM) of China was initiated in 2001 and became one of the 31 members of National Science and Technology Resource Sharing Platform in 2019. Currently, NRCMM is co-managed by Model Animal Research Center of Nanjing University and Gempharmatech (GPT, a Shanghai Exchange enlisted public company). Dedicated to produce and collect genetic edited mouse models, NRCMM holds more than 22,000 mouse strains in 2024, compared with 18,500 strains reported in 2022. This review provides an update on our Knock-Out All Project (KOAP) and highlights resources available for immune system reconstitution models, disease models, and chromosome substitution strains at NRCMM.

Indexed as

Disease Models, AnimalMice, Mutant StrainsAnimalsChinaGene EditingMiceMice, KnockoutMutation

Identifiers

PMID40146303
PMCPMC12130089

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.