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ArticlePediatric cardiology2026

A Case of Indolent Kawasaki Disease with Delayed Coronary Artery Lesions: The Role of Proactive Imaging.

Koji Nishigaki, Kunihiko Takahashi, Shota Hamano, Masaki Ota, Ayuka Kato, Kyoko Noguchi, Taisuke Onoe, Shizuka Nishimoto, Makiko Kikkawa, Yasuyuki Tokunaga and 1 more

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In one paragraph

Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Koji NishigakiDepartment of Pediatrics, Toyonaka Municipal Hospital, 4-14-1 Shibaharacho, Toyonaka, Osaka, 560-8565, Japan.
Kunihiko TakahashiDepartment of Pediatrics, Toyonaka Municipal Hospital, 4-14-1 Shibaharacho, Toyonaka, Osaka, 560-8565, Japan. kunitaka@chp.toyonaka.osaka.jp.
Shota HamanoDepartment of Pediatrics, Toyonaka Municipal Hospital, 4-14-1 Shibaharacho, Toyonaka, Osaka, 560-8565, Japan.
Masaki OtaDepartment of Pediatrics, Toyonaka Municipal Hospital, 4-14-1 Shibaharacho, Toyonaka, Osaka, 560-8565, Japan.
Ayuka KatoDepartment of Pediatrics, Toyonaka Municipal Hospital, 4-14-1 Shibaharacho, Toyonaka, Osaka, 560-8565, Japan.
Kyoko NoguchiDepartment of Pediatrics, Toyonaka Municipal Hospital, 4-14-1 Shibaharacho, Toyonaka, Osaka, 560-8565, Japan.
Taisuke OnoeDepartment of Pediatrics, Toyonaka Municipal Hospital, 4-14-1 Shibaharacho, Toyonaka, Osaka, 560-8565, Japan.
Shizuka NishimotoDepartment of Pediatrics, Toyonaka Municipal Hospital, 4-14-1 Shibaharacho, Toyonaka, Osaka, 560-8565, Japan.
Makiko KikkawaDepartment of Pediatrics, Toyonaka Municipal Hospital, 4-14-1 Shibaharacho, Toyonaka, Osaka, 560-8565, Japan.
Yasuyuki TokunagaDepartment of Pediatrics, Toyonaka Municipal Hospital, 4-14-1 Shibaharacho, Toyonaka, Osaka, 560-8565, Japan.
Kosuke ChayamaDepartment of Pediatrics, Toyonaka Municipal Hospital, 4-14-1 Shibaharacho, Toyonaka, Osaka, 560-8565, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kawasaki Disease (KD) is an acute vasculitis primarily affecting children and can lead to coronary artery lesions (CALs) if not promptly diagnosed and treated. Indolent KD, characterized by spontaneous fever resolution without early intervention, poses diagnostic challenges as patients may not initially meet the complete diagnostic criteria, delaying treatment and increasing the risk of CAL development. We report a case of a 17-month-old boy with indolent KD who developed CAL on the 18th day of illness, necessitating IVIG therapy. Despite initial symptom resolution, echocardiographic monitoring revealed delayed coronary artery involvement, underscoring the importance of proactive imaging. This case highlights the need for frequent echocardiographic evaluation in indolent KD, particularly when clinical and laboratory findings are inconclusive. Serial imaging facilitates early detection of CALs, enabling timely IVIG therapy and potentially preventing disease progression. A structured follow-up strategy is crucial in managing indolent KD to reduce the risk of long-term cardiovascular complications.

Indexed as

Coronary Artery DiseaseCoronary VesselsMucocutaneous Lymph Node SyndromeEchocardiographyHumansImmunoglobulins, IntravenousInfantMaleImmunoglobulins, IntravenousCoronary artery lesions (CALs)EchocardiographyIndolent Kawasaki diseaseIntravenous immunoglobulin (IVIG)Kawasaki diseaseLow C-reactive protein (CRP)

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.