Evidence map›Paper›PMID 40146008›Full record

ArticleMedical physics2025

Evaluation of novel detector readout modes for MV scatter reduction on kV images.

Ha Nguyen, Mathias Lehmann, Daniel Morf, Jason Luce, Andrew Keeler, Hyejoo Kang, John C Roeske

Abstract readEvaluation Study
In one paragraph

Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ha NguyenDepartment of Radiation Oncology, Stritch School of Medicine, Cardinal Bernadin Cancer Center, Loyola University Chicago, Maywood, Illinois, USA.
Mathias LehmannVarian Medical System, Palo Alto, California, USA.
Daniel MorfVarian Medical System, Palo Alto, California, USA.
Jason LuceDepartment of Radiation Oncology, Stritch School of Medicine, Cardinal Bernadin Cancer Center, Loyola University Chicago, Maywood, Illinois, USA.
Andrew KeelerDepartment of Radiation Oncology, Stritch School of Medicine, Cardinal Bernadin Cancer Center, Loyola University Chicago, Maywood, Illinois, USA.
Hyejoo KangDepartment of Radiation Oncology, Stritch School of Medicine, Cardinal Bernadin Cancer Center, Loyola University Chicago, Maywood, Illinois, USA.
John C RoeskeDepartment of Radiation Oncology, Stritch School of Medicine, Cardinal Bernadin Cancer Center, Loyola University Chicago, Maywood, Illinois, USA.

Funding

Markerless Motion Tracking of Lung Tumors Using Dual Energy ImagingR01CA207483 · NCI · LOYOLA UNIVERSITY CHICAGO · PI LEHMANN, MATHIAS, ROESKE, JOHN · 2017 to 2025
$2.2M
National Cancer Institute of the National Institutes of Health R01-CA207483NCI NIH HHS R01 CA207483
6 · The paper itself

Abstract

backgroundThere is increased interest in concurrent kilovoltage (kV) imaging during megavoltage (MV) irradiation as a means of monitoring intra-fraction motion. However, scatter introduced by the MV beam degrades kV image quality, potentially making tumor visualization more challenging. PURPOSE: To implement novel imager readout modes on the on-board imager (OBI) of a Varian TrueBeam to reduce the effect of MV scatter on the kV detector.

methodsNew readout strategies (vertical 3 × 2 binning, vertical region of interest, kV pulse drop functionality) were incorporated to achieve high frame rates. A series of 120 kV images were acquired on the OBI while simultaneously irradiating a phantom with an MV beam (6xFFF and 10xFFF) with field sizes ranging from 2 × 2 cm

resultsThe amount of MV scatter was directly proportional to the square field size and the detector integration time. At their respective maximum dose rates, 6xFFF and 10xFFF produced comparable amounts of MV scatter for considered frame rates and field sizes. Increasing the frame rates from 7 to 45 fps decreased MV scatter by up to 87%. Over the same frame rates, the CNR was improved by 20% for the 2 × 2 cm

conclusionsMV scatter onto the kV detector can be significantly reduced with the implementation of the new detector readout modes. These strategies increase the CNR and thus improve the image quality.

Indexed as

Image Processing, Computer-AssistedScattering, RadiationPhantoms, ImagingSignal-To-Noise Ratioimage‐guided radiation therapyintra‐fractional imagingmegavoltage scatteron‐board imagerradiation

Identifiers

PMID40146008
PMCPMC13105157

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.