ReviewJournal of virology2025
Highly pathogenic avian influenza H5N1: history, current situation, and outlook.
Review in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
84 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Circulation of avian influenza viruses in migratory birds in Europe and in Africa: a systematic review.Emerging microbes & infections · 2026Pooled it
- Mapping Reported Modes of Transmission of Highly Pathogenic Avian Influenza A (H5N1) to Humans: A Scoping Review.One health (Amsterdam, Netherlands) · 2026Review
- Respiratory pandemic risk in the Anthropocene: A One Health framework and GISRS+ agenda.One health (Amsterdam, Netherlands) · 2026Review
- Infection of ratites with clade 2.3.4.4b HPAIV H5N1: potential implications for zoonotic risk.Emerging microbes & infections · 2026Article
- Airway organoids reveal patterns of influenza A tropism and adaptation in wildlife species.Emerging microbes & infections · 2026Article
- Modeling and control of highly pathogenic avian influenza in poultry using network disease dynamics.Infectious Disease Modelling · 2026Article
- A phylogeny-informed mathematical modeling of HPAI H5N1 transmission dynamics and effectiveness of control measures.One health (Amsterdam, Netherlands) · 2026Article
- Streamlined CRISPR-based assays for detection and subtyping of H5 and H7 avian influenza.iScience · 2026Article
- Reassortment of Highly Pathogenic Avian Influenza as a Driver for Zoonotic Spillover, Asia.Emerging infectious diseases · 2026Review
- Will there be a warning for the next pandemic?Science advances · 2026Article
- Enhanced induction of inflammatory cytokines in human lung cells infected with highly pathogenic recent H5N1/2024 avian influenza virus.Archives of virology · 2026Article
- Development of a multi-species luciferase-based double-antigen ELISA for the detection of antibodies against influenza A virus H5 clade 2.3.4.4b.Journal of clinical microbiology · 2026Article
- Epidemiological and Phylogenetic Analysis of Reassorted H10Nx Avian Influenza Viruses in Guangdong Province, China.Influenza and other respiratory viruses · 2026Article
- A Comparison of Juvenile and Adult Sunflower Sea Star Transcriptomic Responses to Challenge With Sea Star Wasting Disease Tissue Homogenates.Ecology and evolution · 2026Article
- Small molecule inhibition of the mitochondrial lipid transfer protein STARD7 attenuates influenza viral replication.PLoS pathogens · 2026Article
- Tradeoffs between targeted and expanded testing strategies for influenza A(H5N1).ASM case reports · 2026Article
- Isolation and characterization of a clade 2.3.4.4b genotype D1.1 H5N1 virus from dairy cattle in Wisconsin.Journal of virology · 2026Article
- Validation of sample pooling for high-throughput RT-qPCR subtyping of avian influenza A(H5).Microbiology spectrum · 2026Article
- Cellular tropism of highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b viruses in human respiratory and bovine mammary epithelial cells.Microbiology spectrum · 2026Article
- Between-species contagion drives HPAI transmission and mass mortality in seabirds.The Journal of animal ecology · 2026Article
24 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The H5N1 avian panzootic has resulted in cross-species transmission to birds and mammals, causing outbreaks in wildlife, poultry, and US dairy cattle with a range of host-dependent pathogenic outcomes. Although no human-to-human transmission has been observed, the rising number of zoonotic human cases creates opportunities for adaptive mutation or reassortment. This Gem explores the history, evolution, virology, and epidemiology of clade 2.3.4.4b H5N1 relative to its pandemic potential. Pandemic risk reduction measures are urgently required.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.