Evidence map›Paper›PMID 40145639›Full record

ArticleCurrent protocols2025

Isolation and Characterization of Human Tissue Resident Memory T cells.

Isaac J Jensen, Steven B Wells, Julien Gras, Donna L Farber

Abstract read
In one paragraph

Article in Current protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Isaac J JensenDepartment of Microbiology and Immunology, Columbia University Irving Medical Center, New York.
Steven B WellsDepartment of Microbiology and Immunology, Columbia University Irving Medical Center, New York.
Julien GrasDepartment of Microbiology and Immunology, Columbia University Irving Medical Center, New York.
Donna L FarberDepartment of Microbiology and Immunology, Columbia University Irving Medical Center, New York.ORCID https://orcid.org/0000-0001-8236-9183

Funding

Transcriptomics and Repertoire ProfilingP01AI106697 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Donna L. Farber · 2013 to 2026
$31.3M
Training in Translational Immunology ResearchT32AI148099 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SYKES, MEGAN · 2020 to 2024
$1.4M
NIAID NIH HHS P01 AI106697NIAID NIH HHS T32 AI148099
6 · The paper itself

Abstract

The majority of immune cells in the human body exist within the tissues rather than in the circulation. Nevertheless, most of our knowledge of the human immune system is biased towards the characterization and understanding of circulating immune cell populations because the latter are readily sampled, whereas cells in tissues are difficult to obtain and/or are limited to single sites of disease. Tissue-resident cells differ from circulating cells due to tissue-specific niche adaptations that influence their phenotype and function. For instance, T cells in tissues, resident memory (T

Indexed as

Cell SeparationImmunologic MemoryMemory T CellsHumanshuman tissueimmune cellssingle cell suspensionT cellstissue resident

Identifiers

PMID40145639
PMCPMC12101136

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.