Evidence map›Paper›PMID 40145553›Full record

ArticleMolecular medicine reports2025

Salidroside ameliorates lipopolysaccharide‑induced ferroptosis in chondrocytes via regulation of the sirt1/foxo1 axis.

Xu Zhang, Ling Huang, Wenjun Feng, Danghan Xu, Yirong Zeng

Abstract read
In one paragraph

Article in Molecular medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xu Zhang1st School of Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510405, P.R. China.
Ling HuangDepartment of Orthopedics, Shunde Third People's Hospital, Guangzhou, Guangdong 528000, P.R. China.
Wenjun FengDepartment of Orthopaedics, First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510405, P.R. China.
Danghan XuDepartment of Orthopaedics, First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510405, P.R. China.
Yirong ZengDepartment of Orthopaedics, First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510405, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salidroside (SAL) is a bioactive constituent extracted from

Indexed as

ChondrocytesFerroptosisForkhead Box Protein O1GlucosidesLipopolysaccharidesPhenolsSignal TransductionSirtuin 1AnimalsApoptosisCells, CulturedCell SurvivalOsteoarthritisForkhead Box Protein O1GlucosidesLipopolysaccharidesPhenolsrhodiolosideSirtuin 1ferroptosisosteoarthritissalidrosidesirt1/foxo1 signaling

Identifiers

PMID40145553
PMCPMC11963749

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.