Evidence map›Paper›PMID 40145486›Full record

Trial reportEuropean endodontic journal2025

Efficacy of Two Different Concentrations of Iodine-potassium Iodide Solution in Endodontic Retreatment: A Randomised Double-blinded Clinical Trial.

Meerna Sarkees, Hisham Alafif, Samar Ali Alsalameh, Hassan Achour

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in European endodontic journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Meerna SarkeesDepartment of Endodontics, Damascus University, Faculty of Dentistry, Damascus, Syria.
Hisham AlafifDepartment of Endodontics, Damascus University, Faculty of Dentistry, Damascus, Syria.
Samar Ali AlsalamehDepartment of Basic Science, Damascus University, Faculty of Dentistry, Damascus, Syria.
Hassan AchourDepartment of Endodontics, Damascus University, Faculty of Dentistry, Damascus, Syria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the antibacterial effectiveness of two concentrations of iodine-potassium iodide (IKI) used as the final irrigating solution during endodontic retreatment.

methodsThirty symptom-free root-filled anterior teeth with chronic apical periodontitis (<5*5mm) were included. They were divided into two groups consisting of 15 teeth according to the method of final irrigation. Group 1 were irrigated with 2% IKI, and Group 2 with 5% IKI. The direct bacterial viable count method was performed to determine the number of colony-forming units (CFUs) before and after disinfection. The reduction in bacterial count was assessed, and statistical analysis was performed using Mann-Whitney U tests with a 95% confidence level.

resultsIrrigation with 5% IKI resulted in significantly reduced bacterial counts than 2% IKI irrigation (p<0.05), indicating greater antibacterial effects.

conclusionThe use of a 5% IKI solution as the final irrigating agent in endodontic retreatment cases with chronic apical periodontitis significantly reduces bacterial counts compared to a 2% IKI solution. The 5% IKI solution therefore exhibited a superior antibacterial effect. Consequently, 5% IKI solution application improves microbiological outcomes and enhances the overall disinfection of the root canal system. (EEJ-2024-08-131).

Indexed as

Iodine CompoundsPeriapical PeriodontitisPotassium IodideRoot Canal IrrigantsAdultDouble-Blind MethodFemaleHumansMaleMiddle AgedRetreatmentRoot Canal TherapyTreatment OutcomeIodine Compoundsiodine potassium iodidePotassium IodideRoot Canal Irrigants

Identifiers

PMID40145486
PMCPMC11971707

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.