Evidence map›Paper›PMID 40145122›Full record

ArticleJHLT open2024

Outcomes of lung transplantation from donors with hepatitis C viremia with outpatient initiation of antiviral therapy.

Ciara M Shaver, Jinyuan Liu, Ke Xu, Gong Yang, Madeline C Morrison, Alexis Goree, Heather O'Dell, Roman Perri, Matthew Bacchetta, Loren Lipworth and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JHLT open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ciara M ShaverDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Jinyuan LiuDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee.
Ke XuDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee.
Gong YangDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Madeline C MorrisonVanderbilt Transplant Center, Vanderbilt University Medical Center, Nashville, Tennessee.
Alexis GoreeVanderbilt Transplant Center, Vanderbilt University Medical Center, Nashville, Tennessee.
Heather O'DellVanderbilt Transplant Center, Vanderbilt University Medical Center, Nashville, Tennessee.
Roman PerriDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Matthew BacchettaDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Loren LipworthDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Anil J TrindadeDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.

Funding

Immunogenomic analysis of donor lung injury and its impact on clinical outcomes after lung transplantationR01HL160551 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ciara M Shaver · 2022 to 2026
$3.4M
Mechanisms of airspace inflammation caused by cell-free hemoglobin during ARDSK08HL136888 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SHAVER, CIARA M · 2017 to 2021
$858k
NHLBI NIH HHS K08 HL136888NHLBI NIH HHS R01 HL160551
6 · The paper itself

Abstract

Transplantation of lungs from donors with active hepatitis C viremia with early initiation of antiviral therapy has been shown to have similar short- and medium-term outcomes compared to transplantation of lungs from nonviremic donors. Consideration of hepatitis C viremic lungs is particularly helpful in patients with anticipated prolonged time on the waiting list. Whether clinical outcomes remain favorable with delay of initiation of antiviral therapy to the outpatient setting or in patients with higher severity of illness is not well understood. Our transplant center considered hepatitis C nucleic acid testing positive (NAT

Indexed as

acute cellular rejectionhepatitis Clung transplantationmortalityoutpatient antiviral therapy

Identifiers

PMID40145122
PMCPMC11935328

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.