Evidence map›Paper›PMID 40145106›Full record

ArticleJHLT open2024

Pulmonary artery pulsatility index predicts mechanical circulatory support following heart transplantation.

Ivan H W Yim, Stephen J Pettit, Sai Bhagra, Marius Berman, Nigel E Drury, Hoong Sern Lim

Abstract read
In one paragraph

Article in JHLT open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ivan H W YimDepartment of Cardiac Surgery, Queen Elizabeth Hospital Birmingham, Birmingham, UK.
Stephen J PettitTransplant Unit, Royal Papworth Hospital, Cambridge, UK.
Sai BhagraTransplant Unit, Royal Papworth Hospital, Cambridge, UK.
Marius BermanTransplant Unit, Royal Papworth Hospital, Cambridge, UK.
Nigel E DruryDepartment of Cardiac Surgery, Queen Elizabeth Hospital Birmingham, Birmingham, UK.
Hoong Sern LimDepartment of Cardiology, Queen Elizabeth Hospital Birmingham, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The incidence of mechanical circulatory support (MCS) for early graft dysfunction (EGD) following heart transplantation varies from 2.3% to 28.2%. Low pulmonary pulsatility index (PAPI) is associated with higher mortality in advanced heart failure and cardiogenic shock. We hypothesized that a lower pulmonary pulsatility index following heart transplantation is associated with MCS use for EGD. Methods: Two-center study of consecutive heart transplantation from May 2018 to December 2022. Hemodynamic parameters and inotropic/vasoconstrictor data were investigated on admission to the intensive care unit (T0) and at 6 hours later (T6). Results: Of the 173 patients included in this study, 24 had MCS for EGD. PAPI in the group that required MCS was lower at T0 (1.21 (0.84) vs 1.67 (1.23), Conclusions: Lower PAPI at T6 (<1.22) is independently associated with MCS use for severe EGD postheart transplantation.

Indexed as

graft dysfunctionheart transplantationmechanical circulatory supportpulmonary artery pressureright ventricular failure

Identifiers

PMID40145106
PMCPMC11935374

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.