Evidence map›Paper›PMID 40145097›Full record

ArticleFrontiers in immunology2025

BCG-derived acellular membrane vesicles elicit antimycobacterial immunity and innate immune memory.

Takehiro Yamaguchi, Noriaki Samukawa, Sohkichi Matsumoto, Masayuki Shiota, Masaki Matsumoto, Ryoma Nakao, Satoru Hirayama, Yutaka Yoshida, Akihito Nishiyama, Yuriko Ozeki and 1 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Takehiro YamaguchiDepartment of Pharmacology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Noriaki SamukawaDepartment of Pharmacology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Sohkichi MatsumotoDepartment of Bacteriology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Masayuki ShiotaDepartment of Molecular Biology of Medicine, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Masaki MatsumotoDepartment of Omics and Systems Biology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Ryoma NakaoDepartment of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan.
Satoru HirayamaDepartment of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan.
Yutaka YoshidaDepartment of Bacteriology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Akihito NishiyamaDepartment of Bacteriology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Yuriko OzekiDepartment of Bacteriology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Shuhei TomitaDepartment of Pharmacology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) is one of the leading causes of death due to infectious disease. The sole established vaccine against TB is the

Indexed as

BCG VaccineExtracellular VesiclesImmunity, InnateImmunologic MemoryMycobacterium bovisTuberculosisAnimalsFemaleMiceMice, Inbred BALB CMice, Inbred C57BLToll-Like Receptor 2Trained ImmunityBCG VaccineTlr2 protein, mouseToll-Like Receptor 2acellular vaccinesBCGmembrane vesicles (MVs)trained immunitytuberculosis

Identifiers

PMID40145097
PMCPMC11937015

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.