Evidence map›Paper›PMID 40145034›Full record

ArticleJHLT open2024

Development of a hub-and-spoke durable left ventricular assist device program in Brazil, a middle-income country.

Deborah de Sá Pereira Belfort, Bruno Biselli, Mônica Samuel Avila, Renata Lopes Hames, Stephanie Itala Rizk, Fabrício Canova Calil, Bruna Carneiro Oliveira, Filomena Regina Barbosa Gomes Galas, Ludhmila Abrahão Hajjar, Nadine Oliveira Clausell and 8 more

Erratum issuedAbstract read
In one paragraph

Article in JHLT open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Deborah de Sá Pereira BelfortHospital Sirio-Libanes, São Paulo, SP, Brazil.
Bruno BiselliHospital Sirio-Libanes, São Paulo, SP, Brazil.
Mônica Samuel AvilaHospital Sirio-Libanes, São Paulo, SP, Brazil.
Renata Lopes HamesHospital Sirio-Libanes, São Paulo, SP, Brazil.
Stephanie Itala RizkHospital Sirio-Libanes, São Paulo, SP, Brazil.
Fabrício Canova CalilHospital Sirio-Libanes, São Paulo, SP, Brazil.
Bruna Carneiro OliveiraHospital Sirio-Libanes, São Paulo, SP, Brazil.
Filomena Regina Barbosa Gomes GalasHospital Sirio-Libanes, São Paulo, SP, Brazil.
Ludhmila Abrahão HajjarHeart Institute (InCor), Instituto do Coração, Hospital das Clinicas, HCFMUSP, Universidade de São Paulo, São Paulo, SP, Brazil.
Nadine Oliveira ClausellHospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Livia Adams GoldraichHospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Ramez AnbarHospital Sirio-Libanes, São Paulo, SP, Brazil.
Edimar Alcides BocchiHospital Sirio-Libanes, São Paulo, SP, Brazil.
Tadeu ThoméHospital Sirio-Libanes, São Paulo, SP, Brazil.
Roberto Kalil FilhoHospital Sirio-Libanes, São Paulo, SP, Brazil.
Paulo Manuel Pêgo-FernandesHospital Sirio-Libanes, São Paulo, SP, Brazil.
Fabio Biscegli JateneHospital Sirio-Libanes, São Paulo, SP, Brazil.
Silvia Moreira Ayub-FerreiraHospital Sirio-Libanes, São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In middle-income countries, costs limit widespred use of left ventricular assist device (LVAD) as a strategy for end-stage heart failure. We aim to describe the experience of a LVAD program in a middle-income country in a hub-and-spoke model. Methods: Patients fulfilling strict inclusion and exclusion criteria were referred from different centers in Brazil for LVAD implantation through a philanthropy program financed via a Brazilian Federal Government tax exemption structure. LVAD implantation was performed in a hub-and-spoke model with a single implanting center. Data were collected retrospectively using hospital records and telephone contact with other centers. Patients who received LVAD implants external to the philanthropic program, either at this or other Brazilian centers, were not included. Results: Between January 1, 2013 and December 31, 2020, 20 adult patients underwent long-term continuous flow LVAD implantation with decentralization of postimplant patient care in regional centers. Patients were referred from 11 centers from 7 states in Brazil and underwent LVAD implantation through a philanthropy program. The median age was 52.5 years and 85% were Interagency Registry for Mechanically Assisted Circulatory Support profile 3 patients. Two patients had Chagas cardiomyopathy. The overall survival censored for competing risks at 1 and 2 years were 90% and 84%, respectively. Three patients (15%) underwent heart transplantation in the first 2 years after LVAD implantation. Twelve patients returned to their original centers and were followed remotely. Conclusions: This study presents a successful LVAD implantation program in a hub-and-spoke model in Brazil. Centralization of LVAD implantation with decentralization of postimplant patient care in regional centers is feasible and safe, enabling optimal allocation of resources in middle-income countries.

Indexed as

heart failurehub-and-spokeleft ventricular assist devicemiddle-income countriessurvival analysis

Identifiers

PMID40145034
PMCPMC11935476

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.