Evidence map›Paper›PMID 40145031›Full record

ArticleJHLT open2024

A multicenter analysis of lung transplantation outcomes comparing donation after circulatory death and donation after brain death.

Mohammed Abul Kashem, Gabriel Loor, Matthew Hartwig, Dirk Van Raemdonck, Mauricio Villavicencio, Fabio Ius, Kamrouz Ghadimi, Jawad Salman, Satish Chandrashekaran, Tiago Machuca and 16 more

Erratum issuedAbstract read
In one paragraph

Article in JHLT open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Association Between Three Lung Donor Scores and Lung Acceptance in DBD and DCD Donors.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  5. Review
  6. Review
  7. Emerging roles for complement in lung transplantation.The Journal of clinical investigation · 2025
    Review
  8. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors.

Mohammed Abul KashemLewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.
Gabriel LoorBaylor College of Medicine, Houston, Texas.
Matthew HartwigDuke University Medical Center, Durham, North Carolina.
Dirk Van RaemdonckUniversity Hospitals Leuven, Leuven, Belgium.
Mauricio VillavicencioMayo Clinic, Rochester, Minnesota.
Fabio IusHannover Medical School, Hannover, Germany.
Kamrouz GhadimiDuke University, Durham, North Carolina.
Jawad SalmanHannover Medical School, Hannover, Germany.
Satish ChandrashekaranEmory University Hospital, Atlanta, Georgia.
Tiago MachucaUniversity of Miami School of Medicine, Miami, Florida.
Pablo G SanchezUniversity of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Kathirvel SubramaniamUniversity of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Arne NeyrinckUniversity Hospitals Leuven, Leuven, Belgium.
Hannah CalvelliLewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.
Michael WarnickLewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.
Huaqing ZhaoLewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.
Stephen HuddlestonUniversity of Minnesota, Minneapolis, Minnesota.
Asishana OshoMassachusetts General Hospital, Boston, Massachusetts.
Ethan D'SilvaBaylor College of Medicine, Houston, Texas.
Uma RamamurthyBaylor College of Medicine, Houston, Texas.
Andres Leon PenaBaylor College of Medicine, Houston, Texas.
Marcelo Salan-GomezBaylor College of Medicine, Houston, Texas.
Andrew ShafferUniversity of Minnesota, Minneapolis, Minnesota.
Nathaniel LangerMassachusetts General Hospital, Boston, Massachusetts.
Amir EmtiazjooUniversity of Florida, Gainesville, Florida.
Yoshiya ToyodaLewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Donor organ shortage is a barrier to lung transplantation. Donation after circulatory death (DCD) may offer a solution, although it is underutilized. The objective of this study was to compare survival and other postoperative outcomes between DCD and donation after brain death (DBD). Methods: We performed a multicenter analysis of Multi-Institutional Extracorporeal Life Support (ECLS) Registry data from 11 lung transplant centers in the United States and Europe. Demographics and clinical parameters were compared using chi-square test and Fisher's exact test. Survival was assessed by Kaplan-Meier curves and compared by log-rank test with propensity score matching. Results: Of 1,585 patients included in the study, 135 (8.5%) received DCD lungs and 1,450 (91.5%) received DBD lungs. DCD recipients had higher rates of obstructive lung disease ( Conclusions: Overall, our data showed excellent 90-day survival for DCD and DBD recipients, although DCD recipients had relatively lower survival. EVLP was not associated with survival, which may guide future strategies to optimize DCD utilization.

Indexed as

donation after brain deathdonation after circulatory deathlung transplantoutcomessurvival

Identifiers

PMID40145031
PMCPMC11935477

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.