Evidence map›Paper›PMID 40145030›Full record

ArticleJHLT open2024

Pulmonary artery banding to treat end-stage heart failure in infants and young children: A multicenter study.

Massimo A Padalino, Domenico Crea, Matteo Ponzoni, Luca Vedovelli, Andrzey Kansy, Thierry Bove, Joseph Panzer, Marc Gewillig, Bjorn Cools, Thomas Salaets and 6 more

Abstract read
In one paragraph

Article in JHLT open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Massimo A PadalinoDepartment of Cardiothoracic and Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Domenico CreaDepartment of Cardiothoracic and Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Matteo PonzoniDepartment of Cardiothoracic and Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Luca VedovelliDepartment of Cardiothoracic and Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Andrzey KansyChildren's Memorial Health Institute Warsaw, Warsaw, Poland.
Thierry BoveKliniekhoofd Hartchirurgie, Department of Cardiac Surgery Universitair Ziekenhuis Gent, University Hospital of Ghent, Ghent,Belgium.
Joseph PanzerKliniekhoofd Kindercardiologie, Department of Pediatrics Universitair Ziekenhuis Gent, University Hospital of Ghent, Ghent, Belgium.
Marc GewilligDepartment of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.
Bjorn CoolsDepartment of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.
Thomas SalaetsDepartment of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.
Dexter ChengThe Medical City Hospital, Manila, Philippines.
Andrea FrancavillaDepartment of Cardiothoracic and Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Alessia CeruttiDepartment of Woman and Child's Health, University of Padova, Padova, Italy.
Vladimiro VidaDepartment of Cardiothoracic and Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Giovanni Di SalvoDepartment of Woman and Child's Health, University of Padova, Padova, Italy.
Biagio CastaldiDepartment of Woman and Child's Health, University of Padova, Padova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Conventional treatment options for end-stage heart failure (ESHF) in children include heart transplantation (HT) and ventricular assist devices (VADs), both with significant drawbacks in the pediatric population. Pulmonary artery banding (PAB) has been effectively used as bridge to transplant or recovery in pediatric ESHF. We herein describe the early and mid-term clinical outcomes from a multicenter international experience. Methods: This is a multicenter retrospective study including children admitted for ESHF caused by dilated cardiomyopathy and treated with PAB. The primary outcome was the freedom from death/VAD/HT. Results: Thirty-one patients (median age 210 days [131-357]) with ESHF underwent PAB in 5 centers. Pediatric Interagency Registry for Mechanically Assisted Circulatory Support (PEDIMACS) score was I to III in 90%; 15 patients were intubated preoperatively. Preoperative left ventricular (LV) ejection fraction was <30% in 68%, with LV dilation in all cases. Postoperatively, median PAB gradient was 29 mm Hg (23-34), and complications occurred in 14 patients (45%), with 4 (13%) early deaths. Twenty-seven patients were successfully discharged home on anti-congestive therapy. At a median follow-up of 2.9 years, there were 1 late death and 3 HTs. Freedom from death/VAD/HT was 77.3% (95% confidence interval [CI] = 58-88.4%), 77.3% (95%CI=58-88.4%), and 73.2% (95%CI=53.2-85.5%) at 6 months, 1 year, and 2 years of follow-up, respectively. All 23 survivors with a native heart had gradual normalization of LV function and dimensions. Conclusions: PAB can be an effective procedure to treat ESHF in selected infants, as alternative strategy for bridging to transplant or recovery.

Indexed as

dilated cardiomyopathyend-stage heart failurelate outcomesmulticenter studypulmonary artery banding

Identifiers

PMID40145030
PMCPMC11935319

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.