Evidence map›Paper›PMID 40145009›Full record

ArticleJournal of surgical case reports2025

Brown tumor causing pathologic fracture of the ipsilateral femur and pelvis in a pregnant woman: a case report.

Kyle Gouveia, Marc D Bouchard, Philip Hache, James R Yan, Snezana Vukmirovic-Popovic, Salem Alowami, Herman Johal

Abstract readCase Reports
In one paragraph

Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kyle GouveiaDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada.
Marc D BouchardFaculty of Medicine and Health Sciences, Royal College of Surgeons in Ireland, 123 St Stephen's Green, Dublin 2, D02 YN77, Ireland.ORCID https://orcid.org/0009-0003-6883-9486
Philip HacheDepartment of Orthopaedics, Faculty of Medicine, University of British Columbia, 2775 Laurel Street, Vancouver, BC, V5Z 1M9, Canada.
James R YanDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada.
Snezana Vukmirovic-PopovicDivision of Clinical Pathology, Department of Pathology and Molecular Medicine, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada.
Salem AlowamiDivision of Clinical Pathology, Department of Pathology and Molecular Medicine, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada.
Herman JohalDivision of Orthopaedic Surgery, Department of Surgery, University of Calgary, 3330 Hospital Dr NW, Calgary, AB, T2N 2T8, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 30-year-old pregnant woman who was found to have an aggressive-appearing osteolytic lesion of the left distal femur in the setting of hypercalcemia. Biopsy confirmed a brown tumor secondary to hyperparathyroidism. She underwent a successful parathyroidectomy followed by a Cesarean section. Postpartum, she sustained pathologic fractures of the ipsilateral femur and pelvis due to a fall, requiring operative fixation. She progressed to uncomplicated healing following surgical management. Although brown tumors can appear aggressive on imaging, they typically resolve following treatment of the underlying hyperparathyroidism. Pathologic fractures should be managed according to standard orthopedic principles. Clinicians should include brown tumors in the differential diagnosis when evaluating osteolytic lesions, particularly in the presence of hypercalcemia.

Indexed as

bone lesionbrown tumormultidisciplinary carepathologic fracturepregnancyprimary hyperparathyroidism

Identifiers

PMID40145009
PMCPMC11937820

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.