Evidence map›Paper›PMID 40144839›Full record

ReviewJHLT open2025

Lung transplantation for pulmonary chronic graft-versus-host disease: a missed opportunity?

Andrea Zajacova, Hélène Schoemans, Mark Greer, Hildegard Greinix, Peter Jaksch, Osnat Shtraichman, Rayid Abdulqawi, Are M Holm, Robin Vos, Saskia Bos

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrea ZajacovaDepartment of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium.
Hélène SchoemansDepartment of Haematology, Bone marrow Transplant Unit, University Hospitals Leuven, Leuven, Belgium.
Mark GreerDepartment of Respiratory Medicine & Infectious Diseases, Hannover Medical School, Hannover, Germany.
Hildegard GreinixDivision of Haematology Medical University Graz, Graz, Austria.
Peter JakschDepartment of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.
Osnat ShtraichmanPulmonary Institute, Rabin Medical Center, Affiliated with Sackler School of Medicine Tel Aviv University, Petach Tikva, Israel.
Rayid AbdulqawiLung Health Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia.
Are M HolmDept of Respiratory Medicine, Oslo University Hospital, Oslo, Norway.
Robin VosDepartment of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium.
Saskia BosDepartment of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic graft-versus-host disease is a common complication after allogeneic hematopoietic stem cell transplantation, with pulmonary chronic graft-versus-host disease (PcGvHD) particularly associated with a dismal prognosis. Lung transplantation (LuTx) is a final therapeutic option for well-selected patients affected by this condition. Nevertheless, only a small group of PcGvHD patients are referred for LuTx. This review addresses common concerns regarding referral and listing of PcGvHD patients for LuTx (such as risk of relapse of hematological malignancy, infectious complications and rejection) and survival outcomes of this specific cohort of patients. Importantly, LuTx for PcGvHD has comparable outcomes to other indications. The establishment of specific LuTx indication criteria for PcGvHD patients may improve referral rates and timing of both referral and listing of suitable candidates.

Indexed as

Bronchiolitis obliteransGvHDLung transplantationPulmonary graft-versus-host diseaseRestrictive allograft syndromeSyndrome

Identifiers

PMID40144839
PMCPMC11935357

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.