Evidence map›Paper›PMID 40144837›Full record

ArticleJHLT open2025

Disturbed sleep after lung transplantation is associated with worse patient-reported outcomes and chronic lung allograft dysfunction.

Aric A Prather, Ying Gao, Legna Betancourt, Rose C Kordahl, Anya Sriram, Chiung-Yu Huang, Steven R Hays, Jasleen Kukreja, Daniel R Calabrese, Aida Venado and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Aric A PratherDepartment of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, California.
Ying GaoDepartment of Medicine, University of California San Francisco, San Francisco, California.
Legna BetancourtDepartment of Medicine, University of California San Francisco, San Francisco, California.
Rose C KordahlDepartment of Medicine, University of California San Francisco, San Francisco, California.
Anya SriramDepartment of Medicine, University of California San Francisco, San Francisco, California.
Chiung-Yu HuangDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California.
Steven R HaysDepartment of Medicine, University of California San Francisco, San Francisco, California.
Jasleen KukrejaDepartment of Surgery, University of California San Francisco, San Francisco, California.
Daniel R CalabreseDepartment of Medicine, University of California San Francisco, San Francisco, California.
Aida VenadoDepartment of Medicine, University of California San Francisco, San Francisco, California.
Bhavya KapseDepartment of Medicine, University of California San Francisco, San Francisco, California.
John R GreenlandDepartment of Medicine, University of California San Francisco, San Francisco, California.
Jonathan P SingerDepartment of Medicine, University of California San Francisco, San Francisco, California.

Funding

Examining the reciprocal effects of racial discrimination and sleep on cardiovascular functioning: An experimental approachR01HL142051 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PRATHER, ARIC ANDREW · 2018 to 2022
$3.5M
NHLBI NIH HHS R01 HL142051
6 · The paper itself

Abstract

Background: Many lung transplant recipients fail to derive the expected improvements in health-related quality of life (HRQL) and survival. Sleep may represent an important, albeit rarely examined, factor associated with lung transplant outcomes. Methods: Within a larger cohort study, 141 lung transplant recipients completed the Medical Outcomes Study Sleep Problems Index (SPI) Revised scale along with a broader survey of patient-reported outcome (PRO) measures and frailty assessment. From the SPI, we also derived an insomnia-specific subscale. Potential perioperative risk factors for disturbed sleep were derived from medical records. We investigated associations between perioperative predictors on SPI and insomnia and associations between SPI and insomnia on PROs and frailty by linear regressions, adjusting for age, sex, and lung function. We evaluated the associations between SPI and insomnia on time to chronic lung allograft dysfunction (CLAD) and death using Cox models, adjusting for age, sex, and transplant indication. Results: Post-transplant hospital length of stay >30 days was associated with worse sleep by SPI and insomnia (SPI: Conclusions: Poor sleep after lung transplant appears associated with PROs, frailty, CLAD, and death. Clarifying the nature of this association may have important screening implications.

Indexed as

cognitive functioningfrailtyHRQLlung transplantationsleep

Identifiers

PMID40144837
PMCPMC11935370

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.