Evidence map›Paper›PMID 40144817›Full record

ArticleJHLT open2025

Is it safe to proceed with heart transplant in a patient with active tuberculosis? Strategies and challenges based on a case report.

Laura Hastenteufel, Marcelo Basso Gazzana, Nadine Clausell, Lívia Adams Goldraich

Abstract readCase Reports
In one paragraph

Article in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laura HastenteufelHeart Transplant Program, Division of Cardiology, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
Marcelo Basso GazzanaDivision of Pneumology, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
Nadine ClausellHeart Transplant Program, Division of Cardiology, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
Lívia Adams GoldraichHeart Transplant Program, Division of Cardiology, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transplant candidates are at increased risk of developing active tuberculosis (TB), and its diagnosis and treatment may be especially challenging. Although screening and treatment for TB are recommended in heart transplant candidates, there is lack of evidence on how to manage active TB infection in this scenario. Herein, we report challenges of performing a heart transplant in a 69-year-old patient with progressive heart failure and active, symptomatic TB infection. We aimed to emphasize the importance of proper screening of TB in solid organ transplant candidates, as well as to suggest that, in selected patients, it may be safe to proceed with transplant after an initial period of treatment with antituberculous agents.

Indexed as

Active tuberculosisHeart transplant

Identifiers

PMID40144817
PMCPMC11935332

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.