Evidence map›Paper›PMID 40144737›Full record

ArticleFrontiers in artificial intelligence2025

Three-stage registration pipeline for dynamic lung field of chest X-ray images based on convolutional neural networks.

Yingjian Yang, Jie Zheng, Peng Guo, Qi Gao, Yingwei Guo, Ziran Chen, Chengcheng Liu, Tianqi Wu, Zhanglei Ouyang, Huai Chen and 1 more

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Article in Frontiers in artificial intelligence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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3 · Its place in the literature

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4 citing papers in PubMed.

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5 · Who and what money

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11 authors.

Yingjian Yang *Department of Radiological Research and Development, Shenzhen Lanmage Medical Technology Co., Ltd., Shenzhen, Guangdong, China.
Jie Zheng *Department of Radiological Research and Development, Shenzhen Lanmage Medical Technology Co., Ltd., Shenzhen, Guangdong, China.
Peng Guo *Department of Radiological Research and Development, Shenzhen Lanmage Medical Technology Co., Ltd., Shenzhen, Guangdong, China.
Qi GaoNeusoft Medical System Co., Ltd., Shenyang, Liaoning, China.
Yingwei GuoSchool of Electrical and Information Engineering, Northeast Petroleum University, Daqing, China.
Ziran ChenCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang, China.
Chengcheng LiuSchool of Life and Health Management, Shenyang City University, Shenyang, China.
Tianqi WuDepartment of Radiological Research and Development, Shenzhen Lanmage Medical Technology Co., Ltd., Shenzhen, Guangdong, China.
Zhanglei OuyangDepartment of Radiological Research and Development, Shenzhen Lanmage Medical Technology Co., Ltd., Shenzhen, Guangdong, China.
Huai ChenDepartment of Radiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yan KangCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The anatomically constrained registration network (AC-RegNet), which yields anatomically plausible results, has emerged as the state-of-the-art registration architecture for chest X-ray (CXR) images. Nevertheless, accurate lung field registration results may be more favored and exciting than the registration results of the entire CXR images and hold promise for dynamic lung field analysis in clinical practice. Objective: Based on the above, a registration model of the dynamic lung field of CXR images based on AC-RegNet and static CXR images is urgently developed to register these dynamic lung fields for clinical quantitative analysis. Methods: This paper proposes a fully automatic three-stage registration pipeline for the dynamic lung field of CXR images. First, the dynamic lung field mask images are generated from a pre-trained standard lung field segmentation model with the dynamic CXR images. Then, a lung field abstraction model is designed to generate the dynamic lung field images based on the dynamic lung field mask images and their corresponding CXR images. Finally, we propose a three-step registration training method to train the AC-RegNet, obtaining the registration network of the dynamic lung field images (AC-RegNet_V3). Results: The proposed AC-RegNet_V3 with the four basic segmentation networks achieve the mean dice similarity coefficient (DSC) of 0.991, 0.993, 0.993, and 0.993, mean Hausdorff distance (HD) of 12.512, 12.813, 12.449, and 13.661, mean average symmetric surface distance (ASSD) of 0.654, 0.550, 0.572, and 0.564, and mean squared distance (MSD) of 559.098, 577.797, 548.189, and 559.652, respectively. Besides, compared to the dynamic CXR images, the mean DSC of these four basic segmentation networks with AC-RegNet has been significantly improved by 7.2, 7.4, 7.4, and 7.4% ( Conclusion: Our proposed three-stage registration pipeline has demonstrated its effectiveness in dynamic lung field registration. Therefore, it could become a powerful tool for dynamic lung field analysis in clinical practice, such as pulmonary airflow detection and air trapping location.

Indexed as

AC-RegNetanatomical constraintsconvolutional neural networkdynamic chest X-ray imageslung field segmentationmedical image registration

Identifiers

PMID40144737
PMCPMC11936902

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