ArticleJHLT open2025
Similar quality of life after balloon pulmonary angioplasty or pulmonary endarterectomy for CTEPH.
Article in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- ESR Bridges: chronic thromboembolic pulmonary hypertension: new developments in imaging and treatment-a multidisciplinary view.European radiology · 2026Article
- Residual physiological abnormalities after pulmonary endarterectomy and balloon pulmonary angioplasty in CTEPH.PloS one · 2026Article
- Research advances in chronic thromboembolic pulmonary hypertension: from pathological mechanisms to multidisciplinary management.Frontiers in cardiovascular medicine · 2026Review
- Key elements of follow-up care after acute pulmonary embolism focusing on long-term sequelae: a Delphi study among European experts.European heart journal. Quality of care & clinical outcomes · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic thromboembolic pulmonary hypertension (CTEPH) is most commonly treated with pulmonary endarterectomy (PEA) or with a combination of pulmonary vasodilators and balloon pulmonary angioplasty (BPA). Quality of life (QoL) after treatment is one of many factors used to determine which procedure is most suitable for each patient. Studies evaluating QoL after these interventions have not compared QoL between both procedures in a randomized cohort. In this prospective registry study, we explored QoL as an outcome in patients treated with PEA or BPA treatment and which factors correlated to QoL. Methods: CTEPH patients treated in Amsterdam University Medical Center and Aarhus University Hospital, the living with pulmonary hypertension questionnaire (LPHQ) was recorded to assess QoL before treatment and 6 months after treatment. Multiple pulmonary and hemodynamic parameters were recorded as part of standard clinical care. Results: At baseline 99 LPHQ questionnaires were answered and 67 at 6 months. Baseline parameters did not differ significantly between patients undergoing PEA vs BPA. QoL was similar at baseline in both treatment groups, and both groups experienced a similar improvement in QoL after treatment. The New York Heart Association (NYHA) score and Borg score after the six-minute walking distance (6MWD) were most strongly correlated to QoL at all time points. Baseline carbon monoxide diffusion capacity (DLCO) was inversely correlated to QoL after treatment. Presence of residual PH was not associated with significantly decreased QoL. Conclusions: We did not find evidence that QoL differed in 2 separate groups of patients who underwent either BPA or PEA. Multiple parameters pertaining to dyspnea and basic functionality were moderately correlated to QoL, this was not the case for hemodynamic parameters. These results indicate that when determining invasive treatment in CTEPH, QoL can be expected to improve with both treatments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.