Evidence map›Paper›PMID 40144609›Full record

ArticleIndian journal of thoracic and cardiovascular surgery2025

An impetuous "HIT"-sudden blockage of all grafts post CABG.

Jaytesh Parashar, Ganesh Shivnani, Sumir Dubey, Bhupender Singh Bisht, Nadeem Saifi

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Indian journal of thoracic and cardiovascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jaytesh ParasharDepartment of Adult Cardiac Surgery, Sir Gangaram Hospital, Old Rajinder Nagar, New Delhi, India.ORCID 0000-0002-9624-8662
Ganesh ShivnaniDept of Adult Cardiac Surgery, Sir Gangaram Hospital, New Delhi, India.
Sumir DubeyDept of Adult Cardiac Surgery, Sir Gangaram Hospital, New Delhi, India.
Bhupender Singh BishtDepartment of Adult Cardiac Surgery, Sir Gangaram Hospital, Old Rajinder Nagar, New Delhi, India.
Nadeem SaifiDepartment of Adult Cardiac Surgery, Sir Gangaram Hospital, Old Rajinder Nagar, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of hyperacute multiple graft thrombosis following an uneventful coronary artery bypass graft (CABG) surgery in a 69-year-old female with chronic immune thrombocytopenia (ITP). Detailed evaluation revealed the presence of anti-PF4/heparin antibodies, confirming the diagnosis of heparin-induced thrombocytopenia (HIT). The co-existence of chronic ITP masked the thrombocytopenia typically associated with HIT, complicating the recognition of the thrombotic and hematologic abnormalities. This case emphasizes the importance of promptly discontinuing heparin when HIT is suspected or confirmed. Additionally, maintaining a low threshold for suspecting HIT in patients with ITP undergoing cardiac surgery is crucial, as this complex interplay may increase the risk of severe postoperative complications.

Indexed as

Chronic immune thrombocytopenia (ITP)Coronary artery bypass graft (CABG)Graft thrombosisHeparin-induced thrombocytopenia (HIT)

Identifiers

PMID40144609
PMCPMC11933507

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.