Evidence map›Paper›PMID 40144598›Full record

ArticleIndian journal of thoracic and cardiovascular surgery2025

Vasopressin as a postoperative management strategy in Fontan procedure: a comparative study.

Shubhadeep Das, Debasis Das, Nilanjan Dutta, Manish Kumar Sharma, Shivani Gajpal, Susovan Halder, Unmesh Chakraborty, Apu Saha, Bharath Saske, Shubham Gupta

Abstract read
In one paragraph

Article in Indian journal of thoracic and cardiovascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Shubhadeep DasPediatric Cardiac Intensive Care Unit, Narayana Superspeciality Hospital, Howrah, West Bengal India.ORCID 0000-0003-1996-2800
Debasis DasDept. of Cardiac Surgery, Narayana Superspeciality Hospital, Howrah, West Bengal India.
Nilanjan DuttaDept. of Cardiac Surgery, Narayana Superspeciality Hospital, Howrah, West Bengal India.
Manish Kumar SharmaDept. of Cardiac Anesthesiology, Narayana Superspeciality Hospital, Howrah, West Bengal India.
Shivani GajpalDept. of Cardiac Anesthesiology, Narayana Superspeciality Hospital, Howrah, West Bengal India.
Susovan HalderNarayana Superspeciality Hospital, Howrah, West Bengal India.
Unmesh ChakrabortyNarayana Superspeciality Hospital, Howrah, West Bengal India.
Apu SahaNarayana Superspeciality Hospital, Howrah, West Bengal India.
Bharath SaskeNarayana Superspeciality Hospital, Howrah, West Bengal India.
Shubham GuptaNarayana Superspeciality Hospital, Howrah, West Bengal India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The Fontan procedure is crucial for managing univentricular heart conditions but can lead to prolonged pleural effusions, affecting recovery and hospital stays. This study evaluated the effectiveness of vasopressin in reducing pleural effusion and improving recovery outcomes following Fontan procedure. Methods: This comparative observational study reviewed patient records from October 2021 to September 2023. Two cohorts were included of 23 patients each: patients who received postoperative vasopressin from October 2022 to September 2023 (VP group) and a historical control group from the previous year (NVP group), excluding those who underwent fenestrated Fontan. Vasopressin was administered postoperatively to the VP group to mitigate pleural effusion. Primary outcomes were the volume and duration of chest tube drainage. Secondary outcomes included hospital and intensive care unit (ICU) stay durations and fluid balance metrics. Results: There were no significant differences in the primary or secondary outcomes between the vasopressin group and the control group. The median total drain outputs in the VP and NVP groups were 69.4 ml/kg and 53.9 ml/kg, respectively ( Conclusion: Vasopressin does not significantly impact chest tube drainage volume or duration, nor does it reduce hospital stays in Fontan patients, suggesting a limited role in managing postoperative pleural effusions. Further research is needed to explore its benefits for specific patient subgroups and acute hemodynamic instabilities postoperatively. Graphical Abstract: Supplementary Information: Below is the link to the electronic supplementary material. 10.1007/s12055-024-01873-9.

Indexed as

Cardiac surgeryFontan procedurePleural effusionPostoperative careVasopressin

Identifiers

PMID40144598
PMCPMC11933559

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