Evidence map›Paper›PMID 40144454›Full record

ArticleJBMR plus2025

Primary hypertrophic osteoarthropathy: phenotypic variability and penetrance rate in heterozygotes for

Adriano Miguel Arcanjo, Amanda Fernandes de Souza, Elisangela Pereira de Souza Quedas, Joya Emilie de Menezes Correia-Deur, Dalton Libanio Ferreira, Sergio Pereira de Almeida Toledo, Delmar Muniz Lourenço

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JBMR plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. BiallelicFrontiers in endocrinology · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adriano Miguel ArcanjoEndocrine Genetics Unit, Laboratory of Cellular and Molecular Endocrinology (LIM-25), Division of Endocrinology and Metabolism, Hospital das Clínicas (HCFMUSP), University of São Paulo School of Medicine (FMUSP), São Paulo, São Paulo SP, 01246-903, Brazil.
Amanda Fernandes de SouzaEndocrine Genetics Unit, Laboratory of Cellular and Molecular Endocrinology (LIM-25), Division of Endocrinology and Metabolism, Hospital das Clínicas (HCFMUSP), University of São Paulo School of Medicine (FMUSP), São Paulo, São Paulo SP, 01246-903, Brazil.
Elisangela Pereira de Souza QuedasEndocrine Genetics Unit, Laboratory of Cellular and Molecular Endocrinology (LIM-25), Division of Endocrinology and Metabolism, Hospital das Clínicas (HCFMUSP), University of São Paulo School of Medicine (FMUSP), São Paulo, São Paulo SP, 01246-903, Brazil.
Joya Emilie de Menezes Correia-DeurEndocrine Genetics Unit, Laboratory of Cellular and Molecular Endocrinology (LIM-25), Division of Endocrinology and Metabolism, Hospital das Clínicas (HCFMUSP), University of São Paulo School of Medicine (FMUSP), São Paulo, São Paulo SP, 01246-903, Brazil.
Dalton Libanio FerreiraDepartment of Radiology, Hospital das Clínicas (HCFMUSP), University of São Paulo School of Medicine (FMUSP), São Paulo, São Paulo, Brazil.
Sergio Pereira de Almeida ToledoDepartment of Radiology, Hospital das Clínicas (HCFMUSP), University of São Paulo School of Medicine (FMUSP), São Paulo, São Paulo, Brazil.
Delmar Muniz LourençoEndocrine Genetics Unit, Laboratory of Cellular and Molecular Endocrinology (LIM-25), Division of Endocrinology and Metabolism, Hospital das Clínicas (HCFMUSP), University of São Paulo School of Medicine (FMUSP), São Paulo, São Paulo SP, 01246-903, Brazil.ORCID https://orcid.org/0000-0003-1147-4159

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary hypertrophic osteoarthropathy (PHO) is a rare autosomal recessive disease caused by pathogenic variants (PVs) in

Indexed as

cutis verticis gyratamolecular diagnosispachydermoperiostosispenetranceprimary hypertrophic osteoarthropathySLCO2A1 gene

Identifiers

PMID40144454
PMCPMC11937822

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.