ArticleBrain communications2025
Brain structural alterations in vestibular schwannoma beyond tinnitus and hearing loss.
Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain tumours alter brain structures and functions. However, morphometric alterations induced by unilateral vestibular schwannoma, a benign tumour of the vestibulocochlear nerve, have not been extensively explored. Recent studies have suggested that the tumour does not grow bigger following diagnosis in several patients, suggesting an avenue for conservative therapy. This study aims to comprehensively investigate brain structural re-organizations in vestibular schwannoma patients taking into account the effects of hearing loss and tinnitus-the most common symptoms. To this end, preoperative data from 48 vestibular schwannoma pathology-confirmed patients and a healthy control group of 30 volunteers were retrospectively included in this study. The clinical and imaging data from these participants were processed. General linear models were designed to identify tumour-related brain alterations in grey matter volume and cortical thickness, alongside three other surface measures: sulcal depth, gyrification index and fractal dimension. The differences obtained were further analysed for correlation with tumour size and pure tone audiometry. Interestingly, grey matter volume, cortical thickness and for the first time, fractal dimension measures were increased in vestibular schwannoma patients across key frontal regions (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.