Evidence map›Paper›PMID 40144258›Full record

ArticleJHLT open2024

Outcomes of left ventricular assist device implantations at Karolinska University Hospital: A retrospective study.

Abraham Merzo, Magnus Dalén, Ann Hallberg Kristensen, Michael Melin, Jonas Faxén, Robert Edfors, Emil Najjar

Abstract read
In one paragraph

Article in JHLT open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abraham MerzoDepartment of Medicine, Karolinska Institutet, Stockholm, Sweden.
Magnus DalénDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Ann Hallberg KristensenDepartment of Cardiology, Karolinska University Hospital, Stockholm, Sweden.
Michael MelinDepartment of Cardiology, Karolinska University Hospital, Stockholm, Sweden.
Jonas FaxénDepartment of Cardiology, Karolinska University Hospital, Stockholm, Sweden.
Robert EdforsDepartment of Clinical Sciences, Danderyd University Hospital, Division of Cardiovascular Medicine, Karolinska Institute, Stockholm, Sweden.
Emil NajjarDepartment of Medicine, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To descriptively present data and outcomes of left ventricular assist device (LVAD) implantations at Karolinska University Hospital. Methods: Data were collected from consecutive patients ( Results: Median intensive care unit stay and hospital stay after HM3 implantation was 8 (interquartile range [IQR] 6; 15) and 28 days (IQR 22; 36), respectively. In total, 73% underwent ramp test at some point after the implantation. Death from all causes within 30 days postimplantation was 5%. A total of 21 patients (48%) underwent right heart catheterization, at a median of 0.5 years (IQR 0.3; 0.7) after implantation, and all exhibited optimally unloaded left ventricles. During the study period, 34% of the patients were transplanted, 5% were explanted, and 16% died with LVAD. In total, 11% and 5% suffered from early and late right ventricle failures, respectively. Acute renal failure affected 46% and 18% had driveline infection. Spontaneous cerebral hemorrhage and cerebral infarction affected 5% and 7% of the study population, respectively. Gastrointestinal bleeding affected 16%. The median LVAD duration was 10 months (IQR 5; 22). The 1-year survival rate with LVAD was 85%, and the 2-year survival rate was 80%. Conclusions: The results of this low-volume single-center retrospective study on LVAD implantations align with the results of other studies and international registries.

Indexed as

heart failureHeartMate 3heart transplantationleft ventricular assist devicemechanical circulatory support

Identifiers

PMID40144258
PMCPMC11935364

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.