ArticleFrontiers in oral health2025
Ion release dynamics of bioactive resin cement under variable pH conditions.
Article in Frontiers in oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Effect of Remineralization Products on the Microtensile Strength of Universal Dentin Bonding Systems.Dentistry journal · 2025Article
- Calcium, phosphate and fluoride ionic release from dental restorative materials for elderly population: anFrontiers in oral health · 2025Article
- Recent progress in antimicrobial strategies of controlled-release nanomaterials for secondary caries.Frontiers in cellular and infection microbiology · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Understanding the ion release behaviour of bioactive resin cements is essential for evaluating their potential in restorative dentistry. Sustained ion release, especially at cariogenic pH levels, can enhance remineralization and prolong the longevity of dental restorations. This study investigates the influence of pH on the ion release profiles of a bioactive resin cement before and after recharging. Methods: Disk-shaped specimens ( Results: In the pre-recharging phase (Stage 1), calcium ion release was more pronounced at acidic pH (4.5-5.5), particularly in the first five days. Fluoride and phosphate ions also demonstrated higher release at pH 4.5 and 5.5 compared to pH 6.5. Post-recharging (Stage 2) exhibited similar trends, emphasizing the role of regular recharge in sustaining ion availability. The absence of an initial burst release, commonly seen in other bioactive materials, suggests a distinct ion release mechanism in these resin cements. Conclusion: The findings highlight the pH-dependent release characteristics of bioactive resin cements and reinforce the importance of recharging for maintaining their therapeutic potential. The unique release kinetics observed may offer advantages in long-term remineralization strategies for dental restorations.
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Registered trials
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