ArticleThe journal of allergy and clinical immunology. Global2025
Association between orchiectomy and asthma: Insights from 2 population-based cohorts.
Article in The journal of allergy and clinical immunology. Global, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Allergic Rhinitis Amplifies Asthma Risk in Patients With Chronic Rhinosinusitis: A Large-Scale Retrospective Cohort Analysis.International forum of allergy & rhinology · 2026Article
- Obesity and New-Onset Asthma Risk in Chronic Rhinosinusitis: A Population-Based Cohort Study.Laryngoscope investigative otolaryngology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Background: Orchiectomy, which results in hypogonadism, may increase the risk of asthma due to androgen deficiency. Objectives: We aimed to investigate the association between orchiectomy and asthma risk. Methods: Men aged 18 years or older between 1999 and 2016 were identified from the national real-world database IBM-Explorys. We used multivariable logistic regression adjusted for age and body mass index to determine the risk of asthma among individuals who had and had not undergone orchiectomy. To reproduce our findings, we selected men aged 18 years or older with or without a history of orchiectomy who were enrolled in the globally federated TriNetX database as of May 2024. Results: In the IBM-Explorys database, the orchiectomy group had a 2-fold increase in the odds of having asthma (adjusted odds ratio = 2.03 [95% CI = 1.91-2.16]; Conclusion: Patients who have undergone an orchiectomy are at increased risk of developing asthma. More research is needed to determine the mechanisms underlying the relationship between asthma diagnosis and orchiectomy.
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Registered trials
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