ArticleGynecology and minimally invasive therapy
Unilateral or Bilateral Laparoscopic Ovarian Drilling in Polycystic Ovary Syndrome: A Meta-analysis of Randomized Trials.
Article in Gynecology and minimally invasive therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Modulating endoplasmic reticulum stress and NLRP3 inflammasome in polycystic ovary syndrome: a review of natural and synthetic compounds.Inflammopharmacology · 2025Review
- Hippo signaling pathway in polycystic ovary syndrome.Frontiers in endocrinology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: On the first line of polycystic ovary syndrome (PCOS) treatment, ovulation with clomiphene citrate (CC) is induced. However, 25% of patients need alternative therapy. Laparoscopic ovarian drilling (LOD) can result in successive ovulations and is not linked to ovarian hyperstimulation. In this systematic review and meta-analysis, we aimed to consider the efficacy of unilateral LOD (ULOD) versus bilateral LOD (BLOD) for enhancing fertility and improving fertility outcomes in women with CC-resistant. Materials and Methods: A comprehensive literature search was conducted up to July 15, 2023, to identify relevant randomized controlled trials in PubMed, Scopus, Google Scholar, and Cochrane Library databases. Thirteen articles were included in the meta-analysis. After data extraction, we performed a meta-analysis. Results: As the main unit of analysis for each variable, the standardized mean difference was used between the two groups. The random effects model was used for analysis and heterogeneity was assessed by Conclusion: In summary, this meta-analysis did not find a significant difference in the rate of ovulation, pregnancy, miscarriage, and live birth between the two groups. However, LOD could cause damage to the ovarian reserve, but it has long-term effects on improving the menstrual cycle and reproduction. In general, LOD is a significant method for the treatment of infertility in PCOS, which needs further investigation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.