Evidence map›Paper›PMID 40143979›Full record

ArticleGynecology and minimally invasive therapy

Risks of Malignancy among 11,204 Patients with Endometrial Polyp: A Systematic Review and Meta-analysis.

Sarah Al-Rayes, Mariam Mohamed, Eva Suarthana, Hormoz Nassiri Kigloo, Jason Raina, Togas Tulandi

Abstract read
In one paragraph

Article in Gynecology and minimally invasive therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarah Al-RayesFaculty of Medicine and Health Sciences, McGill University, Montreal, Canada.
Mariam MohamedFaculty of Medicine, University of Montreal, Montreal, Canada.
Eva SuarthanaFaculty of Medicine and Health Sciences, McGill University, Montreal, Canada.
Hormoz Nassiri KiglooDepartment of Obstetrics and Gynecology, McGill University, Montreal, Canada.
Jason RainaDepartment of Family Medicine, University of Manitoba, Manitoba, Winnipeg, Canada.
Togas TulandiFaculty of Medicine and Health Sciences, McGill University, Montreal, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To evaluate factors associated with malignancy in patients with endometrial polyps. Materials and Methods: We conducted electronic database research on PubMed, MEDLINE, EMBASE, COCHRANE, and Google Scholar from inception for all studies on endometrial polyp. After removing duplicates, and title and abstract screening, we had a total of 121 articles and 151 others from screening the reference list. Inclusion criteria included peri and postmenopausal women > 45 years diagnosed histopathologically with endometrial polyp(s). We excluded women with a history of endometrial cancer or hysterectomy. Results: Twenty studies were analyzed. Of 11204 patients with endometrial polyp, 287 had malignant polyps (2.75%), 182 (1.8%) had concomitant endometrial hyperplasia with atypia, and 520 (5.2%) had hyperplasia without atypia within the polyp. Menopausal women had a higher risk of pre-malignancy/malignancy than non-menopausal women (OR 5.63 (95CI 3.87, 8.20, Conclusion: In women with endometrial polyp, menopausal age and thickened endometrium might increase the probability while tamoxifen or HRT use might lower the likelihood of endometrial pre-malignancy/malignancy; and the presence of AUB might signal endometrial pre-malignancy/malignancy.

Indexed as

Abnormal uterine bleedingendometrial cancerendometrial hyperplasiaendometrial intraepithelial neoplasiaperimenopausepolyp

Identifiers

PMID40143979
PMCPMC11936404

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.