Evidence map›Paper›PMID 40143896›Full record

ArticleJHLT open2024

Cardiac magnetic resonance evaluation in recipients of hepatitis c virus-infected donor hearts.

J Lukas Laws, Benjamin Palmer, Jonathan H Soslow, Cassandra Hennessy, Richa Gupta, JoAnn Lindenfeld, Jeffrey M Dendy, Dandan Liu, Kelly H Schlendorf, Daniel E Clark and 1 more

Abstract read
In one paragraph

Article in JHLT open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

J Lukas LawsVanderbilt University Medical Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Nashville, Tennessee.
Benjamin PalmerVanderbilt University Medical Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Nashville, Tennessee.
Jonathan H SoslowMonroe Carell Jr. Children's Hospital at Vanderbilt, Thomas P. Graham Division of Pediatric Cardiology, Department of Pediatrics, Nashville, Tennessee.
Cassandra HennessyVanderbilt University Medical Center, Department of Biostatistics, Nashville, Tennessee.
Richa GuptaMedStar Health, Division of Cardiology, Washington, D.C.
JoAnn LindenfeldVanderbilt University Medical Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Nashville, Tennessee.
Jeffrey M DendyVanderbilt University Medical Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Nashville, Tennessee.
Dandan LiuVanderbilt University Medical Center, Department of Biostatistics, Nashville, Tennessee.
Kelly H SchlendorfVanderbilt University Medical Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Nashville, Tennessee.
Daniel E ClarkStanford University, Division of Cardiovascular Medicine, Department of Internal Medicine, Stanford, California.
Sean G HughesVanderbilt University Medical Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Nashville, Tennessee.

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
NCATS NIH HHS UL1 TR002243
6 · The paper itself

Abstract

Hepatitis C virus positive (HCV+) organ donors offer a viable strategy for expansion of the heart donor pool without an increased risk of recipient mortality. Cardiac magnetic resonance imaging (CMR) is an effective tool for graft surveillance in heart transplant (HT) recipients. However, there are no data comparing CMR findings in HT recipients based on donor HCV status. The aim of this propensity score matched case-control study was to evaluate baseline CMR characteristics of HCV+ HT recipients and HCV- HT recipients, as well as compare cardiac allograft structure, function, performance, and tissue characterization between groups. CMR normative values did not differ between groups in matched analysis. There were no significant differences in CMR-derived biventricular function, strain, late gadolinium enhancement, or myocardial tissue characteristics by parametric mapping. This study suggests CMR can be a valuable tool for surveillance in HCV+ HT patients, and abnormalities on imaging should not be attributed to HCV infection.

Indexed as

cardiac imagingcardiac MRIcardiac transplantationgraft surveillancehepatitis C virustransplant rejection

Identifiers

PMID40143896
PMCPMC11935445

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.