Evidence map›Paper›PMID 40143611›Full record

ArticleJournal of fish diseases2025

Expanding Horizons: The First Reported Outbreak of Piscine Lactococcosis in Farmed Gilthead Seabream Sparus aurata in the Northern Tyrrhenian Sea.

Giuseppe Esposito, Giorgia Bignami, Silvia Colussi, Paolo Pastorino, Fabio Bondavalli, Marialetizia Fioravanti, Elena Bozzetta, Pierluigi Acutis, Andrea Valentino, Renzo Rizzi and 2 more

Abstract read
In one paragraph

Article in Journal of fish diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Comparative Molecular and Antimicrobial Analysis ofAnimals : an open access journal from MDPI · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Giuseppe EspositoIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Turin, Italy.
Giorgia BignamiDepartment of Veterinary Medical Sciences, Ozzano dell'Emilia, Italy.
Silvia ColussiIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Turin, Italy.
Paolo PastorinoIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Turin, Italy.
Fabio BondavalliIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Turin, Italy.ORCID https://orcid.org/0000-0002-2065-3063
Marialetizia FioravantiDepartment of Veterinary Medical Sciences, Ozzano dell'Emilia, Italy.
Elena BozzettaIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Turin, Italy.
Pierluigi AcutisIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Turin, Italy.
Andrea ValentinoIndependent Veterinarian, Gaeta, Italy.
Renzo RizziIndependent Biologist, Orbetello, Italy.
Andrea GustinelliDepartment of Veterinary Medical Sciences, Ozzano dell'Emilia, Italy.ORCID https://orcid.org/0000-0002-4249-4278
Marino PrearoIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Turin, Italy.

Funding

National Recovery and Resilience Plan (NRRP), Mission 4 Component 2 Investment 1.4 - Call for tender No. 3138 of 16 December 2021, rectified by Decree n.3175 of 18 December 2021 of Italian Ministry of University and Research funded by the European Union - Next Generation EU. Project code CN_00000033, Concession Decree No. 1034 of 17 June 2022 adopted by the Italian Ministry of University and Research, CUP J33C22001190001 (Department of Veterinary Medical Sciences, Alma Mater Studiorum Univer
6 · The paper itself

Abstract

Piscine lactococcosis, caused by Lactococcus garvieae, has traditionally been reported in rainbow trout and marine fish in specific regions. However, its first outbreak in farmed gilthead seabream Sparus aurata in the northern Tyrrhenian Sea marks a significant expansion in the distribution of the disease. In 2024, a total of 212 gilthead seabream from three different aquaculture facilities, including one offshore farm with floating cages and two land-based tank farms, were subjected to diagnostic exams during mortality outbreaks. Bacterial isolation and molecular identification confirmed L. garvieae in market-size gilthead seabream collected during mortality outbreaks in the warm season or at seawater temperatures > 18°C. Our results highlight the importance of environmental monitoring and pathogen management in preventing piscine lactococcosis. The outbreaks align with previous studies on L. garvieae infections in marine fish, particularly regarding water temperature. The expanding geographic range of the pathogen necessitates further investigation into its ecology, particularly in Mediterranean aquaculture. This study highlights the need for improved biosecurity measures, early detection methods, and tailored vaccination strategies to mitigate the impact of piscine lactococcosis in gilthead seabream farming. Future research should focus on understanding the environmental triggers and host-pathogen interactions to develop more effective control strategies.

Indexed as

Disease OutbreaksFish DiseasesGram-Positive Bacterial InfectionsLactococcusSea BreamAnimalsAquacultureaquaculturebacterial infectiondisease surveillanceenvironmental stressorsItalyLactococcus garvieaemarine ecosystemspathogenesis

Identifiers

PMID40143611
PMCPMC12152297

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.