Evidence map›Paper›PMID 40143347›Full record

ArticleViruses2025

Bunyaviral Cap-Snatching Endonuclease Activity and Inhibition with Baloxavir-like Inhibitors in the Context of Full-Length L Proteins.

Arlo J Loutan, Baiuyan Yang, Gabrielle Connolly, Adam Montoya, Robert J Smiley, Arnab K Chatterjee, Matthias Götte

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Arlo J LoutanDepartment of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2E1, Canada.ORCID 0009-0001-5208-6534
Baiuyan YangCalibr-Skaggs Institute for Innovation Medicines at Scripps Research, La Jolla, CA 92037, USA.
Gabrielle ConnollyCalibr-Skaggs Institute for Innovation Medicines at Scripps Research, La Jolla, CA 92037, USA.
Adam MontoyaCalibr-Skaggs Institute for Innovation Medicines at Scripps Research, La Jolla, CA 92037, USA.
Robert J SmileyDepartment of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2E1, Canada.
Arnab K ChatterjeeCalibr-Skaggs Institute for Innovation Medicines at Scripps Research, La Jolla, CA 92037, USA.
Matthias GötteDepartment of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2E1, Canada.

Funding

Targeting druggable coronavirus proteinsU19AI171443 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI SUMIT K CHANDA, Arnab Kumar Chatterjee · 2022 to 2026
$101.4M
NIAID NIH HHS U19 AI171443NIH HHS 1U19AI171443-01
6 · The paper itself

Abstract

The

Indexed as

Antiviral AgentsBunyaviridaeEndonucleasesEnzyme InhibitorsOxazinesRNA-Dependent RNA PolymeraseThiepinsTriazinesViral ProteinsDibenzothiepinsHumansInfluenza B virusMorpholinesNaphthyridinesPyridonesRNA, ViralAntiviral AgentsbaloxavirDibenzothiepinsEndonucleasesEnzyme InhibitorsMorpholinesNaphthyridinesOxazinesPyridonesRNA-Dependent RNA PolymeraseRNA, ViralThiepinsTriazinesViral Proteinsantiviral compoundsbaloxavirbunyavirusescap-snatchinggel-based assaysnuclease activityRdRprecombinant proteinsviral RNA-dependent RNA polymerase

Identifiers

PMID40143347
PMCPMC11946187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.