Evidence map›Paper›PMID 40143322›Full record

ArticleViruses2025

The Effect of COVID-19 on Arterial Stiffness and Inflammation: A Longitudinal Prospective Study.

Jhony Baissary, Ziad Koberssy, Jared C Durieux, Ornina Atieh, Joviane Daher, Kate Ailstock, Danielle Labbato, Theresa Foster, Michael A Rodgers, Alexander Merheb and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jhony BaissarySchool of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Ziad KoberssySchool of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID 0009-0002-6819-1926
Jared C DurieuxClinical Research Center, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
Ornina AtiehSchool of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID 0009-0004-3112-8944
Joviane DaherSchool of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Kate AilstockDivision of Medical Laboratory Science, School of Health and Rehabilitation Sciences, The Ohio State University, Columbus, OH 43210, USA.
Danielle LabbatoClinical Research Center, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
Theresa FosterClinical Research Center, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
Michael A RodgersClinical Research Center, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
Alexander MerhebHarvard Faculty of Arts and Sciences, Harvard University, Cambridge, MA 02138, USA.
Nicholas T FunderburgDivision of Medical Laboratory Science, School of Health and Rehabilitation Sciences, The Ohio State University, Columbus, OH 43210, USA.
Grace A McComseySchool of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID 0000-0003-2690-8888

Funding

Clinical and Translational Science Collaborative of Northern Ohio, Catalyzing Linkages to Equity in Health (CLE Health)UM1TR004528 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI GRACE A MCCOMSEY · 2023 to 2026
$32.1M
Clinical and Translational Science Collaborative of Northern Ohio UM1TR004528NCATS NIH HHS UM1 TR004528NCATS NIH HHS UM1TR004528
6 · The paper itself

Abstract

Data are limited for assessing the effect of COVID infection on endothelial function, pre- and post-pandemic. The objective of this study was to assess changes in pre-pandemic cardiovascular parameters after COVID-19 infection. This prospective cohort study used EndoPAT2000 Itamar Medical Ltd., Caesarea, Israel, to measure the augmentation index (AI; arterial elasticity) and reactive hyperemic index (RHI; endothelial function). Markers of endothelial function, inflammation, and gut integrity were collected at pre- and post-pandemic visits. COVID-negative and COVID-positive participants were matched on pre-pandemic covariates, and AI ≥ 5.0 was defined as having worse AI. Among the 156 participants, 50% had documented COVID-19 infection. Groups were balanced (

Indexed as

COVID-19InflammationVascular StiffnessAdultAgedBiomarkersFemaleHumansLipoproteins, LDLLongitudinal StudiesMaleMiddle AgedProspective StudiesSARS-CoV-2BiomarkersLipoproteins, LDLoxidized low density lipoproteinarterial stiffnessCOVID-19endothelial functiongut integrityinflammationmetabolic markers

Identifiers

PMID40143322
PMCPMC11945347

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.