Evidence map›Paper›PMID 40143241›Full record

ArticleViruses2025

West Nile Virus Seroprevalence Among Outdoor Workers in Southern Italy: Unveiling Occupational Risks and Public Health Implications.

Angela Stufano, Valentina Schino, Gabriele Sacino, Riccardo Ravallese, Roberto Ravallese, Leonarda De Benedictis, Anna Morea, Roberta Iatta, Simone Giannecchini, Maria A Stincarelli and 3 more

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Angela StufanoInterdisciplinary Department of Medicine, Section of Occupational Medicine, University of Bari, 70124 Bari, Italy.ORCID 0000-0002-9101-7742
Valentina SchinoInterdisciplinary Department of Medicine, Section of Occupational Medicine, University of Bari, 70124 Bari, Italy.ORCID 0009-0004-0930-3881
Gabriele SacinoInterdisciplinary Department of Medicine, Section of Occupational Medicine, University of Bari, 70124 Bari, Italy.ORCID 0009-0004-7231-8496
Riccardo RavalleseInterdisciplinary Department of Medicine, Section of Occupational Medicine, University of Bari, 70124 Bari, Italy.ORCID 0009-0007-9251-6635
Roberto RavalleseInterdisciplinary Department of Medicine, Section of Occupational Medicine, University of Bari, 70124 Bari, Italy.ORCID 0009-0000-8353-6588
Leonarda De BenedictisInterdisciplinary Department of Medicine, Section of Occupational Medicine, University of Bari, 70124 Bari, Italy.
Anna MoreaInterdisciplinary Department of Medicine, Section of Occupational Medicine, University of Bari, 70124 Bari, Italy.
Roberta IattaInterdisciplinary Department of Medicine, Section of Occupational Medicine, University of Bari, 70124 Bari, Italy.ORCID 0000-0003-2386-8542
Simone GiannecchiniDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Firenze, Italy.ORCID 0000-0003-3374-7621
Maria A StincarelliDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Firenze, Italy.
Maria ChironnaInterdisciplinary Department of Medicine, Section of Hygiene, University of Bari, 70124 Bari, Italy.ORCID 0000-0002-1043-1256
Claudia Maria TrombettaDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0000-0001-7229-9919
Piero LovreglioInterdisciplinary Department of Medicine, Section of Occupational Medicine, University of Bari, 70124 Bari, Italy.ORCID 0000-0002-1609-9397

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWest Nile virus (WNV) is a mosquito-borne RNA virus, with birds as reservoirs and humans as incidental hosts. WNV often causes asymptomatic infections, but severe neuroinvasive disease occurs in fewer than 1% of human cases. Recent climatic changes and occupational exposure have increased its spread, particularly in Southern Italy. This study aimed to assess WNV seroprevalence and occupational risks among outdoor workers to guide targeted public health interventions.

methodsThis cross-sectional study was conducted in the Apulia region, southeastern Italy, from November 2023 to April 2024. Participants completed a detailed questionnaire on socio-demographics, occupational exposure, travel history, and health symptoms. Blood samples were analyzed using enzyme-linked immunosorbent assay (ELISA) and neutralization assays to detect WNV-specific antibodies.

results250 outdoor workers in southeastern Italy were recruited, including agricultural workers, veterinarians, forestry workers, and livestock breeders. The latter showed the highest WNV prevalence at 6.5%. Protective measures such as repellent use (β = -0.145, OR = 0.95,

conclusionsThe study highlights the significant occupational risk posed by WNV to outdoor workers involved in livestock breeding in Southern Italy, likely due to their frequent exposure to mosquito-prone environments. Tailored public health strategies and education programs are needed to protect high-risk outdoor workers from WNV, amidst the backdrop of changing climatic conditions that favor increased transmission.

Indexed as

Occupational ExposureWest Nile FeverWest Nile virusAdultAgedAnimalsAntibodies, ViralCross-Sectional StudiesFemaleHumansItalyMaleMiddle AgedPublic HealthRisk FactorsSeroepidemiologic StudiesAntibodies, Virallivestockoccupational medicineoutdoor workersWest Nile virus

Identifiers

PMID40143241
PMCPMC11946618

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.