Evidence map›Paper›PMID 40143157›Full record

ReviewPharmaceuticals (Basel, Switzerland)2025

Extraction Yields of Psilocybin and Psilocin: A Short Review of Current Methods and Their Implications.

Taynah P Galdino, Lucas C Oliveira, Mateus A Luz, Raquel A Jesus, Eunice P N Lima, Maria C M Torres, Katia Sivieri, Victor I Afonso, João M P Q Delgado, Antonio G B Lima and 2 more

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Interpol review of forensic drug chemistry, 2022-2025.Forensic science international. Synergy · 2026
    Review
  2. Review
  3. Surprising Variability in Tryptamine Profiles ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Chemical Composition and Biological Activities ofPharmaceuticals (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Taynah P GaldinoNortheast Biomaterials Evaluation and Development Laboratory, CERTBIO, Academic Unit of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil.
Lucas C OliveiraNortheast Biomaterials Evaluation and Development Laboratory, CERTBIO, Academic Unit of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil.ORCID 0000-0002-0853-3472
Mateus A LuzNortheast Biomaterials Evaluation and Development Laboratory, CERTBIO, Academic Unit of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil.ORCID 0000-0003-1713-4825
Raquel A JesusNortheast Biomaterials Evaluation and Development Laboratory, CERTBIO, Academic Unit of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil.
Eunice P N LimaNortheast Biomaterials Evaluation and Development Laboratory, CERTBIO, Academic Unit of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil.
Maria C M TorresDepartment of Chemistry, State University of Paraíba, Campina Grande 58429-500, Brazil.ORCID 0000-0002-2575-1578
Katia SivieriDepartament of Food and Nutrition, Faculty of Pharmaceutical Sciences, Sao Paulo State University, Araraquara 14800-903, Brazil.
Victor I AfonsoAcademic Unit of Physics, Federal University of Campina Grande, Campina Grande 58429-900, Brazil.ORCID 0000-0002-7815-2042
João M P Q DelgadoCONSTRUCT-GFC, Department of Civil Engineering, Faculty of Engineering, University of Porto, 4200-465 Porto, Portugal.ORCID 0000-0002-1026-4523
Antonio G B LimaMechanical Engineering Department, Federal University of Campina Grande, Campina Grande 58429-900, Brazil.ORCID 0000-0003-1691-1872
Suédina M L SilvaNortheast Biomaterials Evaluation and Development Laboratory, CERTBIO, Academic Unit of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil.ORCID 0000-0002-2073-0989
Marcus V L FookNortheast Biomaterials Evaluation and Development Laboratory, CERTBIO, Academic Unit of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing body of evidence supporting the therapeutic efficacy of psychoactive substances, like psilocybin, has driven significant interest in recent decades due to their low toxicity and potential applications in treating various mental health disorders. However, producing pharmaceutical-grade psilocybin remains challenging, with three primary approaches: chemical synthesis, biosynthesis, and extraction from

Indexed as

extraction methodspsychoactive compoundsyield optimization

Identifiers

PMID40143157
PMCPMC11945839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.