Evidence map›Paper›PMID 40142967›Full record

ArticlePharmaceutics2025

A Quantitative Approach to Potency Testing for Chimeric Antigen Receptor-Encoding Lentiviral Vectors and Autologous CAR-T Cell Products, Using Flow Cytometry.

Juan José Mata-Molanes, Leticia Alserawan, Carolina España, Carla Guijarro, Ana López-Pecino, Hugo Calderón, Ane Altuna, Lorena Pérez-Amill, Nela Klein-González, Carlos Fernández de Larrea and 4 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Juan José Mata-MolanesDepartment of Immunology, CDB, Hospital Clinic de Barcelona (HCB), 08036 Barcelona, Spain.ORCID 0000-0001-8827-5073
Leticia AlserawanDepartment of Immunology, CDB, Hospital Clinic de Barcelona (HCB), 08036 Barcelona, Spain.ORCID 0000-0003-0428-9844
Carolina EspañaDepartment of Immunology, CDB, Hospital Clinic de Barcelona (HCB), 08036 Barcelona, Spain.
Carla GuijarroDepartment of Immunology, CDB, Hospital Clinic de Barcelona (HCB), 08036 Barcelona, Spain.
Ana López-PecinoImmunogenetics and Immunotherapy in Autoinflammatory and Immune Responses Group, Fundació Clínic-IDIBAPS, 08036 Barcelona, Spain.
Hugo CalderónDepartment of Immunology, CDB, Hospital Clinic de Barcelona (HCB), 08036 Barcelona, Spain.ORCID 0000-0002-8902-4302
Ane AltunaImmunogenetics and Immunotherapy in Autoinflammatory and Immune Responses Group, Fundació Clínic-IDIBAPS, 08036 Barcelona, Spain.ORCID 0000-0001-8350-1609
Lorena Pérez-AmillImmunogenetics and Immunotherapy in Autoinflammatory and Immune Responses Group, Fundació Clínic-IDIBAPS, 08036 Barcelona, Spain.
Nela Klein-GonzálezImmunogenetics and Immunotherapy in Autoinflammatory and Immune Responses Group, Fundació Clínic-IDIBAPS, 08036 Barcelona, Spain.
Carlos Fernández de LarreaSchool of Medicine, Universitat de Barcelona (UB), 08036 Barcelona, Spain.ORCID 0000-0003-4930-9255
Europa Azucena González-NavarroDepartment of Immunology, CDB, Hospital Clinic de Barcelona (HCB), 08036 Barcelona, Spain.ORCID 0000-0003-3310-5557
Julio DelgadoSchool of Medicine, Universitat de Barcelona (UB), 08036 Barcelona, Spain.
Manel JuanDepartment of Immunology, CDB, Hospital Clinic de Barcelona (HCB), 08036 Barcelona, Spain.ORCID 0000-0002-3064-1648
Maria CastellaDepartment of Immunology, CDB, Hospital Clinic de Barcelona (HCB), 08036 Barcelona, Spain.ORCID 0000-0003-2062-0373

Funding

Agència de Gestió d'Ajuts Universitaris i de Recerca 2021-SGR-01162Instituto de Salud Carlos III FIS PI23/01316Instituto de Salud Carlos III PIC18/012La Caixa LCF/PR/SP23/52950004Ministerio de Ciencia, Innovación y Universidades Planes Complementarios Z7318
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

analytical method validationATMP developmentchimeric antigen receptorpotency testingT-cell activation

Identifiers

PMID40142967
PMCPMC11944512

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.