Evidence map›Paper›PMID 40142914›Full record

ReviewJournal of clinical medicine2025

Genicular Artery Embolization: A Technical Review of Anatomy, Pathophysiology, Current Experiences, and Future Directions.

Joseph M Brown, Zachary T Vandeveer, Danielle Cadoret, James J Morrison, Younes Jahangiri

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joseph M BrownDivision of Interventional Radiology, Corewell Health West Michigan, Grand Rapids, MI 49503, USA.
Zachary T VandeveerDivision of Interventional Radiology, Corewell Health West Michigan, Grand Rapids, MI 49503, USA.ORCID 0000-0003-1465-3486
Danielle CadoretDivision of Interventional Radiology, Corewell Health West Michigan, Grand Rapids, MI 49503, USA.ORCID 0000-0001-9990-4138
James J MorrisonDivision of Interventional Radiology, Corewell Health West Michigan, Grand Rapids, MI 49503, USA.
Younes JahangiriDivision of Interventional Radiology, Corewell Health West Michigan, Grand Rapids, MI 49503, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genicular artery embolization (GAE) is an emerging minimally invasive procedure for managing knee osteoarthritis (OA), a condition affecting 365 million individuals globally. Initially developed to treat hemarthrosis, GAE selectively embolizes abnormal genicular vasculature, targeting synovial inflammation and reducing neoangiogenesis. This process alleviates pain and improves joint function, providing an alternative for patients with mild-to-moderate OA who are not candidates for surgical interventions due to comorbidities or other factors. Current evidence supports the use of GAE for patients with mild-to-moderate OA who experience persistent symptoms despite conservative treatments such as physical therapy, weight management, or intra-articular injections. The procedure effectively reduces pain, improves functionality, and provides sustained benefits. This review highlights the anatomical principles, procedural techniques, and patient selection criteria for GAE, as well as the clinical evidence supporting its safety and efficacy. It also explores potential future directions for research, including optimizing patient selection, evaluating long-term outcomes, and integrating GAE into routine OA management pathways.

Indexed as

genicular artery embolizationknee osteoarthritistotal knee arthroplasty

Identifiers

PMID40142914
PMCPMC11943379

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.