Evidence map›Paper›PMID 40142583›Full record

ArticleMicroorganisms2025

In Infants with Neuroblastoma Standard Therapy Only Partially Reverts the Fecal Microbiome Dysbiosis Present at Diagnosis.

Maria Valeria Corrias, Eddi Di Marco, Carola Bonaretti, Margherita Squillario, Loredana Amoroso, Massimo Conte, Mirco Ponzoni, Roberto Biassoni

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria Valeria CorriasLaboratory of Experimental Therapies in Oncology, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, 16147 Genova, Italy.ORCID 0000-0002-7316-0772
Eddi Di MarcoCentral Laboratory, IRCCS Istituto Giannina Gaslini, 00161 Genova, Italy.
Carola BonarettiMolecular Diagnostics, IRCCS Istituto Giannina Gaslini, 00161 Genova, Italy.
Margherita SquillarioIRCCS Ospedale Policlinico San Martino, 00161 Genova, Italy.ORCID 0000-0002-6612-3383
Loredana AmorosoOncology Unit, IRCCS Istituto Giannina Gaslini, 00161 Genova, Italy.ORCID 0000-0003-1950-4754
Massimo ConteOncology Unit, IRCCS Istituto Giannina Gaslini, 00161 Genova, Italy.ORCID 0000-0001-9405-7339
Mirco PonzoniLaboratory of Experimental Therapies in Oncology, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, 16147 Genova, Italy.ORCID 0000-0002-6164-4286
Roberto BiassoniMolecular Diagnostics, IRCCS Istituto Giannina Gaslini, 00161 Genova, Italy.

Funding

Italian Ministry of Health Ricerca Corrente
6 · The paper itself

Abstract

The fecal microbiomes of 15 infants with neuroblastoma (NB) at the onset of the disease and after standard-of-care therapy have been prospectively analyzed compared to those of age-matched healthy infants. By applying several algorithms to 16S sequencing, we found that the fecal microbiomes of infants with NB at onset were abundant in

Indexed as

16S sequencingchemotherapyfecal microbiomeinfantsneuroblastoma

Identifiers

PMID40142583
PMCPMC11946756

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.