Evidence map›Paper›PMID 40142547›Full record

ArticleMicroorganisms2025

Outpatient Testing for HIV in Italy, 2018-2023-Preliminary Data.

Claudio Galli, Vincenza Regine, Anna Caraglia, Francesca Centrone, Maria Chironna, Gianluca Cruschelli, Massimo Farinella, Valentina Annachiara Orlando, Chiara Pasqualini, Monia Puglia and 5 more

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Different approaches to HIV confirmation: a survey of three Italian regions.Frontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Claudio GalliIndependent Researcher, 00139 Rome, Italy.ORCID 0000-0002-0804-0387
Vincenza RegineAIDS Operations Center, Department of Infectious Diseases, Italian National Institute of Health, 00161 Rome, Italy.
Anna CaragliaFormer General Directorate of Health Prevention, Ministry of Health, 00144 Rome, Italy.
Francesca CentroneHygiene Operational Unit, Policlinico Consorziale di Bari, 70124 Bari, Italy.ORCID 0000-0003-3018-5408
Maria ChironnaInterdisciplinary Department of Medicine, University of Bari, 70124 Bari, Italy.ORCID 0000-0002-1043-1256
Gianluca CruschelliDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56124 Pisa, Italy.
Massimo FarinellaMario Mieli, LGBTQIA+ Culture Center, 00146 Rome, Italy.
Valentina Annachiara OrlandoInterdisciplinary Department of Medicine, University of Bari, 70124 Bari, Italy.
Chiara PasqualiniPiedmont Regional Service for the Epidemiology of Infectious Diseases (SeREMI), 15121 Alessandria, Italy.
Monia PugliaTuscany Regional Health Agency (Agenzia Regionale di Sanità, ARS), 50141 Florence, Italy.
Lucia PuglieseAIDS Operations Center, Department of Infectious Diseases, Italian National Institute of Health, 00161 Rome, Italy.ORCID 0000-0001-5322-3169
Laura RancilioCaritas Ambrosiana, 20122 Milan, Italy.
Lara TavoschiDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56124 Pisa, Italy.ORCID 0000-0002-2217-4664
Fabio VollerTuscany Regional Health Agency (Agenzia Regionale di Sanità, ARS), 50141 Florence, Italy.
Barbara SuligoiAIDS Operations Center, Department of Infectious Diseases, Italian National Institute of Health, 00161 Rome, Italy.ORCID 0000-0001-9623-7659

Funding

Italian Ministry of Health-CCM CUP I85E24000350005
6 · The paper itself

Abstract

HIV testing is crucial towards the control of the Acquired Immune Deficiency Syndrome (AIDS) epidemic. Monitoring trends of human immunodeficiency virus (HIV) testing over time may help interpret the incidence of new HIV diagnoses and effectiveness of HIV testing strategies. We started a research project aimed at assessing testing rates for HIV infection among Italian outpatients in 2018-2023. Numeric data for screening, confirmatory, and monitoring tests obtained by a national register were compared with the numbers of adult residents, newly diagnosed HIV infections, and patients undergoing treatment. The number of screening tests declined from 1,133,377 in 2018 to 889,972 in 2020 and increased to 1,096,822 in 2023. HIV-RNA tests showed a similar pattern, whereas confirmatory immunoblots did not vary significantly over time. The ratio of screening tests to adult residents was higher in North-West (2.87%) and North-East (2.31%) Italy compared to South Italy and the islands (1.47%), indicating that screening should be enhanced in the latter area. We observed differences between the ratio of screening tests and the incidence of newly diagnosed HIV infections by geographic area. Discrepancies in the number of screening and confirmatory tests needed for each new diagnosis suggest repeated testing on people already diagnosed and possible data reporting issues. The monitoring of HIV screening tests at the national and regional levels can provide essential data to interpret trends in HIV epidemiology and plan relevant testing strategies over time.

Indexed as

diagnostic algorithmsHIV diagnosisHIV epidemiologyHIV testingpopulation screeningsupplemental tests

Identifiers

PMID40142547
PMCPMC11946390

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.