Evidence map›Paper›PMID 40142458›Full record

ArticleMicroorganisms2025

Epidemiological and Entomological Study After the Possible Re-Emergence of Dengue Fever in Croatia, 2024.

Alan Medić, Vladimir Savić, Ana Klobučar, Maja Bogdanić, Marcela Curman Posavec, Diana Nonković, Ljubo Barbić, Ivana Rončević, Vladimir Stevanović, Tatjana Vilibić-Čavlek

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Strain-specific quantification ofFrontiers in insect science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alan MedićDepartment of Epidemiology, Zadar County Institute of Public Health, 23000 Zadar, Croatia.
Vladimir SavićPoultry Center, Croatian Veterinary Institute, 10000 Zagreb, Croatia.ORCID 0000-0003-0398-5346
Ana KlobučarDepartment of Epidemiology, Andrija Štampar Teaching Institute of Public Health, 10000 Zagreb, Croatia.ORCID 0000-0003-3464-6830
Maja BogdanićDepartment of Virology, Croatian Institute of Public Health, 10000 Zagreb, Croatia.
Marcela Curman PosavecDepartment of Epidemiology, Andrija Štampar Teaching Institute of Public Health, 10000 Zagreb, Croatia.
Diana NonkovićDepartment of Epidemiology, Split-Dalmatia County Institute of Public Health, 21000 Split, Croatia.ORCID 0000-0003-0879-3554
Ljubo BarbićDepartment of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0002-5170-947X
Ivana RončevićPoultry Center, Croatian Veterinary Institute, 10000 Zagreb, Croatia.ORCID 0009-0001-0908-5675
Vladimir StevanovićDepartment of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Tatjana Vilibić-ČavlekDepartment of Virology, Croatian Institute of Public Health, 10000 Zagreb, Croatia.ORCID 0000-0002-1877-5547

Funding

European Union Next Generation EU project supported by the Ministry of Science and Education of the Republic of Croatia, of the Croatian Veterinary Institute: Epidemiology of avian flaviviruses in the "One Health" context; FLAVIR NPOO1
6 · The paper itself

Abstract

Autochthonous dengue cases have been continuously recorded in Europe in the past two decades. The first autochthonous dengue case in Croatia was reported in 2010 on the Pelješac Peninsula, while imported cases were recorded continuously thereafter. In 2024, dengue re-emerged in Croatia. An epidemiological and entomological study was conducted after receiving information on dengue virus (DENV) infection in a German tourist probably acquired on Dugi Otok Island in Croatia in May 2024. Serum samples were collected from 30 residents of the Veli Rat region where the patient had stayed. In addition, mosquitoes were collected in the same area. Human samples were tested for the presence of DENV antibodies (ELISA and IFA) and DENV RNA (RT-qPCR), while mosquito samples were tested for DENV RNA (RT-qPCR). DENV IgM or IgG antibodies were found in 8 serum samples, while no one sample was RT-qPCR positive. No cross-reactivity with flaviviruses was detected in seropositive samples, supporting DENV infection. One patient was classified as a confirmed dengue case (IgG seroconversion in paired serum samples) and five as probable cases (IgM detection in a single serum sample). One additional patient, sampled only once, was IgG seropositive. Two of the seropositive individuals reported fever and rash three weeks before testing. The re-emergence of dengue in Croatia highlights the need for continuous monitoring of DENV circulation in both humans and vectors.

Indexed as

Croatiadenguehumansmosquitoes

Identifiers

PMID40142458
PMCPMC11944314

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.