Evidence map›Paper›PMID 40142451›Full record

ArticleMicroorganisms2025

The Reliable Detection of Homocysteine Using a Biosensor Based on Recombinant Cystathionine β-Synthase and Nanoporous Gold.

Zihan Huang, Yan Gao, Lei Zhang, Ting Cai, Ruijun Liu, Xia Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zihan HuangState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Yan GaoState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Lei ZhangState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Ting CaiState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Ruijun LiuState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Xia WangState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.ORCID 0000-0001-5787-2983

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the essential roles of homocysteine (Hcy) and the interference of cysteine in effectively monitoring human health, this study proposed a synergistic effect strategy that combines the unique structural and functional properties of nanoporous gold (NPG) with the selective recognition capability of a recombinant cystathionine β-synthase (CBS) for the sensitive and specific detection of Hcy. The CBS protein with specific catalytic activity for Hcy was successfully produced in recombinant

Indexed as

cystathionine β-synthaseelectrochemical sensorhomocysteinenanoporous gold

Identifiers

PMID40142451
PMCPMC11945188

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.