Evidence map›Paper›PMID 40142435›Full record

ArticleMicroorganisms2025

Risk Factors for Flares and New Lesions of Hidradenitis Suppurativa Following COVID-19 Disease: A Retrospective Cohort Study of 310 Patients in Greece.

Aikaterini I Liakou, Andreas G Tsantes, Evangelia-Konstantina Bompou, Magdalini Kalamata, Efthymia Agiasofitou, Soultana Vladeni, Angeliki Dragoutsou, Konstantina A Tsante, Petros Ioannou, Eleni Chatzidimitriou and 5 more

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In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Aikaterini I Liakou1st Department of Dermatology-Venereology, "Andreas Sygros" Hospital, Medical School, National and Kapodistrian University of Athens, 16121 Athens, Greece.ORCID 0000-0003-3936-8374
Andreas G TsantesLaboratory of Haematology and Blood Bank Unit, "Attikon" Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID 0000-0002-3695-0759
Evangelia-Konstantina Bompou1st Department of Dermatology-Venereology, "Andreas Sygros" Hospital, Medical School, National and Kapodistrian University of Athens, 16121 Athens, Greece.
Magdalini Kalamata1st Department of Dermatology-Venereology, "Andreas Sygros" Hospital, Medical School, National and Kapodistrian University of Athens, 16121 Athens, Greece.
Efthymia Agiasofitou1st Department of Dermatology-Venereology, "Andreas Sygros" Hospital, Medical School, National and Kapodistrian University of Athens, 16121 Athens, Greece.
Soultana Vladeni1st Department of Dermatology-Venereology, "Andreas Sygros" Hospital, Medical School, National and Kapodistrian University of Athens, 16121 Athens, Greece.
Angeliki Dragoutsou1st Department of Dermatology-Venereology, "Andreas Sygros" Hospital, Medical School, National and Kapodistrian University of Athens, 16121 Athens, Greece.
Konstantina A TsanteLaboratory of Haematology and Blood Bank Unit, "Attikon" Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Petros IoannouSchool of Medicine, University of Crete, 71003 Heraklion, Greece.ORCID 0000-0003-1082-5674
Eleni Chatzidimitriou1st Department of Dermatology-Venereology, "Andreas Sygros" Hospital, Medical School, National and Kapodistrian University of Athens, 16121 Athens, Greece.
Ourania Kotsafti1st Department of Dermatology-Venereology, "Andreas Sygros" Hospital, Medical School, National and Kapodistrian University of Athens, 16121 Athens, Greece.ORCID 0000-0003-4459-435X
George SamonisSchool of Medicine, University of Crete, 71003 Heraklion, Greece.
Georgia VrioniDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0003-4766-8238
Stefanos BonovasDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, 20072 Milan, Italy.ORCID 0000-0001-6102-6579
Alexander I Stratigos1st Department of Dermatology-Venereology, "Andreas Sygros" Hospital, Medical School, National and Kapodistrian University of Athens, 16121 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 disease has been associated with flares or new onsets of various autoinflammatory diseases such as psoriasis and atopic dermatitis. Our aim is to investigate the occurrence and risk factors of flares or new onsets of Hidradenitis Suppurativa (HS) following COVID-19 disease.

methodsA retrospective cohort study was performed including 310 patients with HS following COVID-19 disease. Data on the rate of HS flares, new lesions, time of flare onset, and flare duration were recorded. Demographics, clinical characteristics, and treatment parameters were compared between patients with and without HS flares.

resultsHS flares developed in 69 (22.2%) patients, with 14 experiencing their first episode. The median period between COVID-19 and flare onset was 17 days, with a median flare duration of 14 days. For new HS onset, the median period was 9.5 days, and the median duration was 13 days. Biologic treatment was less common in patients with flares (7.2% vs. 23.2%,

conclusionsCOVID-19 may trigger HS flares and new onset, with biologic treatment and vaccination offering protection.

Indexed as

autoinflammatory disorderscytokinesepidemiologyhidradenitis suppurativaimmunologyinfectionvirology

Identifiers

PMID40142435
PMCPMC11945965

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.