ArticleMicroorganisms2025
Relevancy Prediction of the Emerging Pathogens with Porcine Diarrhea by Logistic Regression Model.
Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Development and clinical validation of a multiplex visual POCT platform based on RT-RAA-CRISPR/Cas12a for porcine diarrheal viruses.Synthetic and systems biotechnology · 2026Article
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Authors and funding
7 authors.
Funding
Abstract
Porcine viral diarrhea has always been one of the main obstacles to the healthy development of the pig industry in China with its variety of pathogens and complexity of co-infections. Analysis of the dominant mixed-infection model is a fundamental step in boosting the prevention and control of porcine diarrhea. In this study, 3256 porcine fecal samples were collected from 17 pig herds in Shanghai, China, from 2015 to 2023 to identify novel pathogenic infection patterns. The results confirmed that porcine astrovirus (PAstV), porcine sapelovirus (PSV), and porcine epidemic diarrhea virus (PEDV) were the top three agents with positive rates of 28.47%, 20.71%, and 20.23%, respectively. Porcine rotavirus (PoRV) and transmissible gastroenteritis virus (TGEV) accounted for only 8.12% and 1.12%, respectively. Importantly, mixed infection rates were high and complicated. The double infection rate was higher than that of a single infection. Next, the mixed-infection model of PEDV and emerging diarrheal pathogens was explored. The predominant dual-infection models were PEDV/PKoV (porcine kobuvirus) (14.18%), PEDV/PAstV (10.02%), and PEDV/PSV (9.29%). The predominant triple infection models were PEDV/PKoV/PAstV (18.93%), PEDV/PSV/PAstV (10.65%), and PEDV/PKoV/PSV (7.10%). The dominant quadruple-infection model was PEDV/PAstV/PSV/PKoV (46.82%). In conclusion, PEDV is mainly mix-infected with PAstV, PSV, and PKoV in clinical settings. Furthermore, multiple-factor logistic regression analysis confirmed that PAstV, PKoV, bovine viral diarrhea virus (BVDV), and PEDV were closely related to porcine diarrhea. PEDV/PKoV, PEDV/porcine sapovirus (PoSaV), PKoV/BVDV, PoSaV/BVDV, and porcine deltacoronavirus (PDCoV)/PoSaV had great co-infection dominance, which will be helpful for porcine co-infection research.
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